Results 11 to 20 of about 121,193 (99)

Production of d-Branched-Chain Amino Acids by Lactic Acid Bacteria Carrying Homologs to Isoleucine 2-Epimerase of Lactobacillus buchneri

open access: yesFrontiers in Microbiology, 2018
Isoleucine 2-epimerase (ILEP) is a novel branched-chain amino acid racemase isolated from Lactobacillus buchneri. In this study, we examined production of free d-branched-chain amino acids such as d-valine, d-leucine, and d-allo-isoleucine, using lactic ...
Yuta Mutaguchi, Kano Kasuga, Ikuo Kojima
doaj   +1 more source

BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer

open access: yesEBioMedicine, 2017
Branched-chain amino acids catabolism plays an important role in human cancers. Colorectal cancer is the third most commonly diagnosed cancer in males and the second in females, and the new global incidence is over 1.2 million cases. The branched-chain α-
Peipei Xue   +17 more
doaj   +1 more source

Branched-Chain Amino Acids and Branched-Chain Keto Acids in Hyperammonemic States: Metabolism and as Supplements

open access: yesMetabolites, 2020
In hyperammonemic states, such as liver cirrhosis, urea cycle disorders, and strenuous exercise, the catabolism of branched-chain amino acids (BCAAs; leucine, isoleucine, and valine) is activated and BCAA concentrations decrease.
Milan Holeček
doaj   +1 more source

Setting the Stage for Branched-Chain Amino Acids Use in Neurological Pathologies: Does a Single Oral Dose Provide Hours of Elevated Systemic Levels?

open access: yesDiseases
Background: Recent studies have demonstrated that branched-chain amino acids are neuroprotective and neurorestorative. Branched-chain amino acid supplements are now being recommended to be taken before contact sports to reduce concussions.
Ezek Mathew   +4 more
doaj   +1 more source

Dataset describing the amino acid catabolism of Thermoanaerobacter pseudethanolicus

open access: yesData in Brief
The dataset depicts the catabolism of branched-chain amino acids by Thermoanaerobacter pseudethanolicus in the presence of thiosulfate under different culture conditions. The results reveal that the strain can degrade all three branched-chain amino acids
Johann Orlygsson, Sean Michael Scully
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 3, Revision 2 (FGE.03Rev2): Acetals of branched‐ and straight‐chain aliphatic saturated primary alcohols and branched‐ and straight‐chain saturated or unsaturated aldehydes, an ester of a hemiacetal and an orthoester of formic acid, from chemical groups 1, 2 and 4

open access: yesEFSA Journal, 2011
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate one flavouring substance, acetaldehyde ethyl isopropyl acetal [FL‐no: 06.137], structurally related to the 58 ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Production and characterization of murine models of classic and intermediate maple syrup urine disease

open access: yesBMC Medical Genetics, 2006
Background Maple Syrup Urine Disease (MSUD) is an inborn error of metabolism caused by a deficiency of branched-chain keto acid dehydrogenase. MSUD has several clinical phenotypes depending on the degree of enzyme deficiency.
Watkins Simon   +4 more
doaj   +1 more source

Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes

open access: yesCell Reports, 2023
Summary: Branched-chain amino acid (BCAA) metabolism is linked to glucose homeostasis, but the underlying signaling mechanisms are unclear. We find that gluconeogenesis is reduced in mice deficient of Ppm1k, a positive regulator of BCAA catabolism, which
Kiyoto Nishi   +10 more
doaj   +1 more source

Comparative analysis of natural rubber and isoprene rubber branched chain structures

open access: yesHecheng xiangjiao gongye
The branched chain structures of imported natural rubber RSS-1 and isoprene rubber molecular chains were compared and analyzed by nuclear magnetic resonance spectrometer.
LI Ze-chun1, QI Xing-guo1, XIANG Jian1, LIAO Shuang-quan2, YANG Chang-jin2
doaj   +1 more source

Isolated branched-chain amino acid intake and muscle protein synthesis in humans: a biochemical review

open access: yesEinstein (São Paulo)
Alongside a proper diet, ergogenic aids with potential direct and/or indirect physical performance enhancing effects are sought after for improved adaptation to physical training.
Carina de Sousa Santos   +1 more
doaj   +1 more source

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