Results 111 to 120 of about 1,870,217 (293)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
External Sovereignty and International Law [PDF]
, 1995 This essay addresses the need to redefine current notions of sovereignty. It returns to earlier concepts of subjects joining to receive the benefits of peace and security provided by the sovereign.
Brand, Ronald A.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Idealist theories of sport in relation to art
Journal of Aesthetics & Culture, 2018 If what can be described as “ideal” in relation to art may be somewhat abstract, then in this article I will apply the basic notion that the ideal is that which links the invisible (thought-content) and visible (the form, “frame”, “vessel”) to that of ...
Danny Shorkend
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Online Video Contest Effects on Brand and Ad Attitudes [PDF]
, 2010 This research investigates how online video contests (OVCs) affect brand image, as measured by brand and advertisement attitudes. After conducting a pre-test to discover an appropriate product for the Generation Y target market, we ran an experiment ...
Janis, Daniel A.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Understanding the 2.5th dimension: modelling the graphic language of products [PDF]
, 2011 Recognizing a product of a specific brand without seeing the logo is difficult. But for companies it is important to distinguish themselves from competitors with a consistent portfolio, which will be easily recognized by their target consumers.
Eggink, Wouter, Mulder-Nijkamp, Maaike
core +1 more source
PERFORMA, 2018 Persaingan yang semakin ketat di industri fashion menuntut perusahaan untuk menciptakan brand equity yang kuat di pasaran. Indo Sejahtera merupakan perusahaan yang menyediakan pakaian bayi dengan brand Happy Baby. Perusahaan beranggapan bahwa kurang dikenalnya brand happy baby sangat mempengaruhi kestabilan penjualan.
openaire +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source