Results 41 to 50 of about 11,199 (260)

Brand-to-generic oxcarbazepine switch – A prospective observational study

Epilepsy Research, 2019
To determine the clinical outcomes of brand-to- generic oxcarbazepine (OXC) switch in patients with epilepsy.This prospective observational study included 103 patients treated with OXC in the tertiary outpatient epilepsy clinic. In 2016 the price of the brand-name OXC in Poland increased by 10 times in comparison to the generic products.
Bosak, Magdalena, Słowik, Agnieszka, Dziedzic, Tomasz   +2 more
openaire   +4 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Consumer Choice Behavior during a Social Disruption [PDF]

Problems and Perspectives in Management, 2017
This paper explores the relationship between an external socio-disruptive factor and consumer product and brand decision-making behavior. The social disruption was physical relocation, which resulted in a radical change in the toilet system, which had ...
Krishna K. Govender
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Resistance To Brand Switching: The Elderly Consumer

Journal of Business & Economics Research (JBER), 2010
In this study, the authors examine one more aspect of the elderly consumer’s brand loyalty: resistance to brand switching. This study claims that elderly consumers are not only more likely to repurchase but also actively resist switching brands once they have established a favorite brand.
Komal Gyani Karani, Katherine A. Fraccastoro   +1 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The Influence of Brand Image and Variety Seeking on Dana E-Wallet Brand Moving Through Consumer Satisfaction as an Intervening Variable in FEB UPN "Veteran" Jawa Timur Students

Indonesian Interdisciplinary Journal of Sharia Economics
This study aims to analyze the impact of Brand image, variety-seeking behavior, and consumer satisfaction on the brand switching of the DANA e-wallet among students of the Faculty of Economics and Business at UPN "Veteran" East Java.
Maharani Huzaema, Rizky Dermawan, Ratih Mukti Azhar   +2 more
doaj   +1 more source

Commitment and Switching Intentions: Customers and Brands

Revista Ibero-Americana de Estratégia, 2012
This study aims to evaluate the relationship between a customer’s brand switching intentions and his commitment to a brand. Based on a literature review, constructs related to customer brand commitment were identified (affective and continuance commitment, trust, satisfaction, switching costs and alternative attractiveness) and their roles in the ...
Rodrigues, Juliana Werneck, da Silva, Jorge Ferreira, Ferreira, Jorge Brantes, Hor-Meyll, Luis Fernando   +3 more
openaire   +3 more sources