N‐of‐1 trials offer a unique and rigorous methodology for evaluating individualized treatment responses, particularly within the context of personalized medicine. This article provides a comprehensive explanation of the conceptual and methodological underpinnings of N‐of‐1 trials, with particular emphasis on statistical techniques and considerations ...
Marcos Clint Leal De Carvalho +5 more
wiley +1 more source
Financial Instability and Credit Constraint: Evidence from the Cost of Bank Financing [PDF]
This paper examines the relation between the degree of firms’ financial constraint and the observed rise in the cost of bank financing during the global financial crisis of 2008.
Bruno S. Martins
core
Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis
Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras +8 more
wiley +1 more source
Purchase of food from the new staple food basket in low-income Brazilian households. [PDF]
Silva MALD +4 more
europepmc +1 more source
Strategies for stimulating poverty-alleviating growth in the rural nonfarm economy in developing countries: [PDF]
"The rural nonfarm economy (RNFE) accounts for roughly 25 percent of full-time rural employment and 35-40 percent of rural incomes across the developing world.
Haggblade, Steven +2 more
core
Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra +8 more
wiley +1 more source
Climate change, food insecurity, and the impacts on child health and nutrition in Brazil: proposal for a conceptual model. [PDF]
Santos-Degner LA +8 more
europepmc +1 more source
CONSEQUENCES OF TRADE LIBERALIZATION ON POVERTY AND INCOME DISTRIBUTION IN BRAZIL [PDF]
This study evaluates the regional short run impacts of reduction in import tariffs in Brazil on poverty and distribution of income related to recent free trade area agreements. Results show that trade can reduce inter-regional income inequality, but poor
Bittencourt, Mauricio V.L. +2 more
core +1 more source
Smartphone addiction among adolescents: associations with mental health, physical inactivity, daytime sleepiness, and consumption of ultra-processed foods. [PDF]
Amaral LL +7 more
europepmc +1 more source
Justice‐centred climate change education and territory
Abstract In a globalised world, education faces challenges that go far beyond professional training, where social responsibility and the inclusion of heterogeneous communities and territories in all levels of education have become a greater focus of the university and of scientific research, setting the stage for more inclusive public policies. Greater
Lennin Florez‐Leiva +3 more
wiley +1 more source

