Results 221 to 230 of about 65,986 (255)

Triazole‐Linked Pyrimidine Nucleoside Dimers: Design, Synthesis, and Applications in Medicinal and Nucleic Acid Chemistry. Part IV

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
A series of 18 pyrimidine nucleoside dimers analogues with a short 1,4‐disubstituted 1,2,3‐triazole linkage were synthesized using a click chemistry approach (CuAAC). Analysis of the obtained products was conducted utilizing 1D/2D NMR spectroscopy (1H, 13C, 19F, 15N, and 29Si), mass spectrometry (ESI‐MS), and high‐performance liquid chromatography ...
Dagmara Baraniak, Dariusz Wawrzyniak, Daniel Baranowski   +2 more
wiley   +1 more source

Adaptive Surgical Decision-Making for Synchronous Metastatic Pancreatic Cancer and Early Breast Cancer with a BRCA1 Pathogenic Variant: A Case Report. [PDF]

Surg Case Rep
Akahori T, Yokotani T, Yoshizawa A, Uchiyama T, Yamaguchi R, Sho M.   +5 more
europepmc   +1 more source

The evolving role of immunotherapy in ovarian cancer

Cancer, Volume 132, Issue 18, 15 September 2026.
Abstract Ovarian cancer remains a major cause of gynecologic cancer mortality; and, although immune checkpoint inhibitors have transformed treatment in other solid tumors, their activity in ovarian cancer has been limited by tumor heterogeneity, an immunosuppressive tumor microenvironment, and the lack of robust predictive biomarkers.
Ana Carolina Veneziani, Laura Venegas, Amit M. Oza   +2 more
wiley   +1 more source

UNC93B1 drives IL-6/STAT3-dependent tumor-macrophage crosstalk and epithelial-mesenchymal transition in breast cancer. [PDF]

Front Pharmacol
Li X, Hao H.
europepmc   +1 more source

BRCA1/2-stratified immune profiling of treatment-naive high-grade serous ovarian cancer ascites identifies a Treg-enriched ascitic immune phenotype. [PDF]

J Pathol Transl Med
Sharma M, Kaur B, Rai B, Sachdeva MUS, Sharma AR, Gupta P, Gautam U, Bagga R, Srinivasan R.   +8 more
europepmc   +1 more source

[Effect of Cancer Antigen-125 Elimination Rate Constant K and <i>BRCA</i> Mutation Status on the Prognosis of Interval Debulking Surgery in Advanced High-Grade Serous Ovarian Cancer]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Li Y, Li M, Zhang X, Xu H, Li J, Liu H, Peng C.   +6 more
europepmc   +1 more source

Platinum Rechallenge in Platinum-Resistant Ovarian Cancer: Clinical Outcomes and the Impact of BRCA Status. [PDF]

Cancers (Basel)
García-Illescas D, Navarro V, Fariñas-Madrid L, García-Durán C, Grau Béjar JF, Musacchio L, Mazzeo R, Giannubilo I, Villacampa G, Oaknin A.   +9 more
europepmc   +1 more source

Integrating in silico modeling and experimental validation to determine the anti-breast cancer mechanisms of mulberry leaf bioactive compounds. [PDF]

Am J Cancer Res
Zhang J, Zhao G, Zhang R, Fu Z, Chen X, Wu J.   +5 more
europepmc   +1 more source

BRCA Testing in Prostate Cancer: A Histopathologist's Perspective. [PDF]

Diagnostics (Basel)
Sanguedolce F, Mazzucchelli R, Conteduca V, Maiorano BA.   +3 more
europepmc   +1 more source

Immune-associated alternative splicing signatures define molecular subtypes in breast cancer. [PDF]

iScience
Liu Y, Wang P, Yuan B, Zhou P, Sun Q.
europepmc   +1 more source