Results 21 to 30 of about 49,034 (223)
Journal of Inflammation Research, 2022 Wang N, Gu Y, Li L, et al. J Inflamm Res. 2022;15:3477–3499. The authors have advised due to an error that occurred inadvertently at the time of figure assembly, the scratch test result of si-SDC1 MBA-MD-231 cells were wrongly placed in the ...
Wang N +6 more
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Pharmacogenomics and Personalized Medicine, 2020 Shira Peleg Hasson,1 Tehillah Menes,2 Amir Sonnenblick1 1Oncology Department, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 2Department of Surgery, Tel Aviv-Sourasky Medical Center and Sackler ...
Peleg Hasson S, Menes T, Sonnenblick A
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JOP : Journal of the pancreas, 2013 Germline mutations in BRCA genes have been associated with pancreatic cancer. Laboratory and clinical data suggest that patients with BRCA mutations may be more responsive to therapy consisting of conventional chemotherapy with a poly(ADP-ribose) polymerase inhibitor (PARPi).
Gregory T, Brennan +2 more
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Pancreatic Cancer: Beyond Brca Mutations
Journal of Personalized Medicine, 2022 Pancreatic cancer is the fourth-leading cause of cancer-related deaths worldwide. The outcomes in patients with pancreatic cancer remain unsatisfactory. In the current review, we summarize the genetic and epigenetic architecture of metastatic pancreatic cancer beyond the BRCA mutations, focusing on the genetic alterations and the molecular pathology in
Vincenzo Ricci +7 more
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Pleura and Peritoneum, 2023 The aim of this study is to analyze the prevalence of somatic mutations in BRCA1 and BRCA2 in malignant mesothelioma and their putative impact on protein properties.
Krishnamurthy Kritika +4 more
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, 2023 BRCA1 and BRCA2 genes encode proteins that have important roles in DNA repair and act as tumor suppressors. Though the sequence and structure of the proteins produced by BRCA1 and BRCA2 are different, they have similar biological activities. Both BRCA gene products are reported to interact with the RAD51 protein, which is essential for DNA repair ...
Bhargavi, Pulukuri, Divya +5 more
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Cancer Management and Research, 2020 Mei Zhan,1– 3 Hanrui Zheng,1– 3 Yu Yang,2,4 Zhiyao He,1 Ting Xu,1,3 Qiu Li2,4 1Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2West China Biomedical Big Data Center, Sichuan ...
Zhan M +5 more
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3D And 2D RNA Structure Prediction Of The BRCA2 Gene And Its Silencing RNA In The Breast Cancer
Walisongo Journal of Chemistry, 2020 Breast cancer is one of the most threatening diseases for women. It is found that BRCA2 gene plays a significant role in breast cancer, provided that mutations occurred.
Ryan Wijaya +2 more
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Genetic predisposition for ovarian cancer development [PDF]
Arhiv za farmacijuOvarian cancer is a leading malignancy in the female reproductive system and is responsible for more deaths than any other type of cancer affecting this system. Ovarian cancers can be hereditary or sporadic.
Joksić Ivana +4 more
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