Results 101 to 110 of about 65,232 (224)
Journal of Clinical Nursing, EarlyView.ABSTRACT Aims To explore the experiences and challenges associated with genetic testing decisions among untested individuals from hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) families. Design Qualitative descriptive study. Methods Semi‐structured telephone interviews were conducted between 2022 and 2024 with 56 untested at‐risk ...
Ronit G. Tsemach +8 more
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Aim The objective of this study was to investigate the global profile of plasmatic proteins of individuals affected simultaneously or not by type 2 diabetes mellitus (T2DM, well/poorly‐controlled), Dyslipidemia (DL), and Periodontitis (P). Methods Besides periodontal examination, plasma was collected for glycemic, and lipid analyses from 150 ...
François Isnaldo Dias Caldeira +7 more
wiley +1 more source
Сибирский онкологический журналBackground. A significant proportion of patients with breast cancer (BC) and ovarian cancer (OC) are carriers of pathogenic variants in the genes of hereditary cancer syndromes. Most often, hereditary forms of BC and OC are associated with alterations in
M. M. Ibragimbekova +11 more
doaj +1 more source
Early but Quality Diagnosis: On Breast Cancer and Its Risk Factors [Letter]
Breast Cancer: Targets and Therapy, 2023 Syeda Sakina Zehra, Zoha Turabee, Mohadisa Asif Rawalia Karachi Medical and Dental College, Karachi, PakistanCorrespondence: Syeda Sakina Zehra, Tel +92 3322609216, Email szehra362@gmail ...
Zehra SS, Turabee Z, Rawalia MA
doaj
An Update on Early‐Onset Breast Cancer: Incidence, Risk Factors, Genetic Testing, and Treatment
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Early‐onset breast cancer presents in patients typically under the age of 40, while very early‐onset breast cancer is usually viewed as breast cancer occurring before the age of 35. Early‐onset breast cancer demonstrates specific molecular properties and has worse outcomes compared to its late‐onset breast cancer counterpart.
Leila Jahangiri
wiley +1 more source
Южно-Российский онкологический журналInherited mutations in the BRCA1/BRCA2 genes significantly increase the risk of breast and ovarian cancer in women of reproductive age, posing a clinical and socioeconomic challenge due to loss of fertility during cancer treatment and preventive ...
S. I. Mikhailov +15 more
doaj +1 more source
Brca2 is involved in meiosis in Arabidopsis thaliana as suggested by its interaction with Dmc1 [PDF]
, 2004 Two BRCA2-like sequences are present in the Arabidopsis genome. Both genes are expressed in flower buds and encode nearly identical proteins, which contain four BRC motifs.
Takvorian, Najat +7 more
core +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Inherited factors account for a large share of breast cancer susceptibility, yet the biological consequences of most risk variants are still poorly understood. To address this gap, we studied 175 breast cancer risk variants confirmed by genome‐wide association studies and gathered the genes that lie near them.
Sultana Jannat +11 more
wiley +1 more source
Patient Preference and Adherence, 2021 Nick Spindler,1 Franziska Ebel,1 Susanne Briest,2 Sandra Wallochny,2 Stefan Langer1 1Department of Orthopedic Surgery, Traumatology and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany; 2Department of Gynecology, Women’s and Children ...
Spindler N +4 more
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International Journal of Cancer, Volume 159, Issue 10, Page 2562-2574, 15 November 2026.While current guidelines recommend the analysis of established cancer driver genes in brain metastases, little is known about its real‐life implementation. This multicenter study revealed an upward trend in the profiling rates of surgically treated brain metastases over the past decade, with up to 60% of brain metastases samples undergoing analysis ...
Maria Nikolaeva +25 more
wiley +1 more source