Results 151 to 160 of about 104,745 (290)
Origin and distribution of the BRCA2-8765delAG mutation in breast cancer [PDF]
, 2007 Background: The BRCA2-8765delAG mutation was firstly described in breast cancer families from French-Canadian and Jewish-Yemenite populations; it was then reported as a founder mutation in Sardinian families.
Baldinu, Paola +10 more
core
A Collaborative Approach to Pediatric Genetic Evaluation in the Era of Genomic Medicine
American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 371-378, February 2026.ABSTRACT To address the increased demand for genetic services and shortage of medical geneticists (MG), a collaborative pilot program was developed with a two‐part approach to care: (1) Initial genetic counselor (GC) appointment with exome sequencing (ES) and (2) follow‐up MG evaluation.
Sarah Jurgensmeyer Langas +5 more
wiley +1 more source
BRCA1 and BRCA2 mutation analysis in 86 early onset breast/ovarian cancer patients. [PDF]
, 1997 Alex M. Garvin +2 more
openalex +1 more source
Survival outcomes in prostate cancer patients treated at an Indian tertiary care centre
BJUI Compass, Volume 7, Issue 2, February 2026.Abstract Background Prostate cancer is an emerging public health concern in India, with rising incidence and varying survival outcomes. This study aimed to evaluate 5‐year overall survival and identify prognostic factors among prostate cancer patients treated at Tata Memorial Hospital (TMH), Mumbai.
Aswathy P +12 more
wiley +1 more source
Posttranscriptional regulation of PARG mRNA by HuR facilitates DNA repair and resistance to PARP inhibitors [PDF]
, 2017 The majority of pancreatic ductal adenocarcinomas (PDAC) rely on the mRNA stability factor HuR (ELAV-L1) to drive cancer growth and progression. Here, we show that CRISPR-Cas9–mediated silencing of the HuR locus increases the relative sensitivity of PDAC
Brody, Jonathan R. +17 more
core +1 more source
BRCA2--Branching Out Too? [PDF]
JNCI Journal of the National Cancer Institute, 2015 Margaret R, Spitz +2 more
openaire +2 more sources
Breast Events After Treatment of Ductal Carcinoma In Situ in Women: A Population‐Based Study
Cancer Medicine, Volume 15, Issue 2, February 2026.ABSTRACT Background Despite favourable survival prognosis, the main concern for ductal carcinoma in situ (DCIS) is local recurrence, especially progression to invasive cancer. This study identified factors associated with breast events following DCIS treatment.
Qian Chen +5 more
wiley +1 more source
41P BRCA2 pathogenic variant (PV): A novel agnostic biomarker for immune checkpoint blockers (ICB)? [PDF]
, 2023 Beatriz Alonso de Castro +17 more
openalex +1 more source
Cancer, Volume 132, Issue 3, 1 February 2026.Abstract Background Germline pathogenic variants can inform targeted therapy for metastatic prostate cancer (mPC), and improve cancer early detection and risk reduction for family members. Guidelines recommend germline genetic testing be offered to all men with mPC, yet uptake of testing is only 10%–12%. Methods This prospective study enrolled veterans
Bruce Montgomery +18 more
wiley +1 more source