Results 171 to 180 of about 65,232 (224)

Messenger RNA From Canine Cytology Lymph Node Specimens Can Be Utilised for Gene Expression Profiling Using Digital RNA Counting

Veterinary and Comparative Oncology, Volume 24, Issue 3, Page 568-577, September 2026.
ABSTRACT Gene expression profiling (GEP) is being used with increasing frequency to characterise canine tumours, but canine samples are often not collected in a medium to preserve RNA. Cytology samples from human tumours have been shown to provide adequate RNA for GEP using NanoString nCounter technology, suggesting a similar approach might be viable ...
McKenzie Olsen, Emily Rout, Kelly Hughes, Janna Yoshimoto, Anne Avery, R. Adam Harris   +5 more
wiley   +1 more source

Double heterozygous germline pathogenic variants in patients referred to a tertiary cancer genetics clinic in Singapore. [PDF]

Front Oncol
Wong RSJ, Ong PY, Ow SGW, Walsh RJ, Chan G, Lim VPY, Lee SC.   +6 more
europepmc   +1 more source

<i>BRCA1</i> Gene as a Potential Marker for Lung Cancer Therapy. [PDF]

Int J Mol Sci
Tsyganov MM, Tsydenova IA, Dolgasheva DS, Ibragimova MK.   +3 more
europepmc   +1 more source

Next-generation sequencing-based characterization of BRCA1/2 variants across multiple tumor types in Vietnamese patients. [PDF]

BMC Cancer
Nguyen HT, Vu MD, Nguyen DD, Dinh PN, Hoang VQ, Bui LN, Nguyen DT, Do PH, Tong TO, Nguyen VH, Han TT, Ha ST, Do HD, Ly TT, Nguyen VN.   +14 more
europepmc   +1 more source

HELZ-BRCA2 complex resolves R-loops to drive transcription-coupled homologous recombination. [PDF]

Nat Commun
Li W, Wu B, Gao B, Irvin EM, Ghosh A, Eliaz L, Huang Y, Kwon Y, Stiefel CM, Nguyen TTN, Zhao D, Suarez HJ, Ni T, Alejo S, Fitzgerald O, Song X, Rath SK, Wasmuth EV, Yu DS, Zheng S, Leung J, Xue X, Wang H, Ji JH, Lan L, Zhao W.   +25 more
europepmc   +1 more source

Distinct functions of mammalian RAD51 paralogs in genome maintenance. [PDF]

Biochem Soc Trans
Dwivedi HK, Bhattacharya D, Kadupatil S, Nagaraju G.   +3 more
europepmc   +1 more source

Reclassification of a BRCA2 variant, c.8487G > A (p.Gln2829Gln) located at 3' end of exon 19, from uncertain significance to likely pathogenic based on splicing alteration: a case report. [PDF]

Jpn J Clin Oncol
Sasaki R, Eguchi H, Yoshioka S, Nakano S, Kato S, Aruga T, Kutomi G, Arai M.   +7 more
europepmc   +1 more source

Clinical Impact of Germline Pathogenic Variants in High-risk Prostate Cancer Treated with Radiotherapy. [PDF]

Eur Urol Open Sci
Galego-Carro J, Santamariña M, Blanco-Pérez A, Aguado-Barrera ME, Amigo J, Fuentes-Ríos O, Coedo-Costa C, Calvo-Crespo P, Peleteiro-Higuero P, Carballo-Castro AM, Taboada-Valladares B, Gómez-Caamaño A, Vega A.   +12 more
europepmc   +1 more source

Homologous recombination deficiency-driven genomic instability in ovarian cancer as an indicator of BRCA1 and BRCA2 variant pathogenicity. [PDF]

Am J Hum Genet
Schnaiter S, Santer FR, Csanaky KA, Jensen LA, Zeimet AG, Michailidou K, Spurdle AB, Thomassen M.   +7 more
europepmc   +1 more source

DNA-contact mutant p53 displaces BRCA2 from chromatin and drives R-loop-associated genome instability. [PDF]

Genome Biol
Li F, Fang K, Si S, Zhang Q, Fan M, Guo C, Sun J, Xie Z, Chen K, Chen Z, Ge Z, Lin C, Luo Z.   +12 more
europepmc   +1 more source