Results 181 to 190 of about 60,203 (254)

Exploring alternatives to tumor tissue for BRCA1/2 next-generation sequencing testing in high-grade serous ovarian cancer: A 34-case series of malignant ascites. [PDF]

Cancer Cytopathol
Pighi C, Settanni G, Angelini M, Bortesi L, Viassolo V, Ceccaroni M, Bruni F, Gori S, Zannoni GF, Pesci A.   +9 more
europepmc   +1 more source

Differential sensitivity of MCPH1- and BRCA2-deficient cancer cells to PARP-1 inhibition. [PDF]

PLoS One
Chapman IG, Wu X, Veuger S, Jowsey PA.
europepmc   +1 more source

Breast cancer risk genes affecting individual radiosensitivity. [PDF]

Sci Rep
Vogel RKG, Amann N, Kassem TZ, Gaß P, Mayo T, Woltereck F, Hack CC, Fietkau R, Corradini S, Distel L, Kuhlmann LCF.   +10 more
europepmc   +1 more source

A comparative study of molecular characteristics of pathogenic and uncertain significance variants of BRCA1/2 in Chinese breast cancer patients. [PDF]

BMC Res Notes
Guan J, Hu J, Lin S, Chen C, Luo Y, Zhou W.   +5 more
europepmc   +1 more source

BRCA1 and BRCA2 pathogenic variants increase the risk of four less common cancer types. [PDF]

ESMO Open
Sasagawa H, Endo M, Iwasaki Y, Usui Y, Koyanagi YN, Innella G, Hadler J, Parsons MT, Numakura K, Kamatani Y, Murakami Y, Matsuo K, Matsuda K, Spurdle AB, Habuchi T, Momozawa Y.   +15 more
europepmc   +1 more source

From Germline Susceptibility to Therapeutic Vulnerability: DNA Damage Response Gene Mutations Driving Multiple Myeloma Evolution and Precision Therapy. [PDF]

Hum Mutat
Shen Q, Wang Y, Cai L, Qian J.
europepmc   +1 more source

Prevalence of recurrent and non-recurrent BRCA1 and BRCA2 pathogenic variants in Polish breast cancer patients: insights from a regional genetic testing cohort from Lower Silesia. [PDF]

BMC Cancer
Matkowski R, Abrahamowska M, Michalowska D, Chrusciel A, Szelachowska J, Blomka D, Lawicka P, Czykalko E, Pietron A, Ekiert M, Doraczynska-Kowalik A, Janus-Szymanska G, Kasprzak P, Szynglarewicz B, Laczmanska I.   +14 more
europepmc   +1 more source

From mutation to treatment: The dual role of BRCA1 and BRCA2 in gynecological malignancy development and management a systematic review. [PDF]

Biochem Biophys Rep
Georgy DM, Sedeek HN, Abaza NE, Eldeeb SEK, Khamis SM, Elgamil MR, Magar RW.   +6 more
europepmc   +1 more source

Combining multiplexed assays of variant effect for enhanced BRCA2 variant classification. [PDF]

Nat Commun
Hu C, Sahu S, Chen W, Galloux M, Richardson ME, Bishop MF, Karam R, Pesaran T, Na J, Huang H, Weitzel JN, Nathanson KN, Yadav S, Boddicker NJ, Domchek SM, Monteiro AN, Iversen ES, Sharan SK, Couch FJ.   +18 more
europepmc   +1 more source

Correction: A comprehensive and accessible model for co-segregation analysis in BRCA1, BRCA2, and PALB2 variant classification. [PDF]

Hum Genet
Moghadasi S, Monajemi R, Braspenning ME, Vreeswijk MPG, Rodríguez-Girondo M.   +4 more
europepmc   +1 more source