Results 181 to 190 of about 46,564 (215)

Structural insights into BRCA2 function

Current Opinion in Structural Biology, 2003
BRCA2 is a tumor suppressor directly implicated in familial breast cancer. Extensive genetic and biochemical characterization has shown that BRCA2 is involved in the maintenance of chromosomal stability and that it has an important role in recombination-mediated double-strand DNA break repair.
openaire   +2 more sources

?????????????? 6174deIT ?? ???????? BRCA2 ?? ???????????? ?? ???????????????????? ?????????????????? ?????????????????? (?????????????????? ??????????????)

2019
Aim: the results of clinical, clinico-genealogical and molecular-genetic investigation of patients from family with tumor aggregation in two generations were analyzed. Object and methods: the data on proband, her parents and sisters were included to the analyses.
openaire   +1 more source

BRCA2

2011
openaire   +2 more sources

Brca2

1998
Tak W. Mak, Josef Penninger, John Roder, Janet Rossant, Mary Saunders   +4 more
openaire   +1 more source

BRCA2

2006
openaire   +2 more sources

Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study

Lancet, The, 2000
Steven A Narod, Mark E Robson, Ketil R Heimdal   +2 more
exaly  

Presymptomatic DNA testing and prophylactic surgery in families with a BRCA1 or BRCA2 mutation

Lancet, The, 2000
Maaike P G Vreeswijk
exaly  

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

Lancet, The, 2010
Michael Friedlander, Clare L Scott, Jeffrey N Weitzel   +2 more
exaly  

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

Lancet, The, 2010
Andrew N J Tutt, Mark E Robson, Susan M Domchek   +2 more
exaly  

Brca2

2018
openaire   +1 more source