Results 201 to 210 of about 60,203 (254)

Repression of EGFR by new biguanide 4C potentiated ovarian cancer to PARP inhibitors through down-regulation of BRCA2 and Rad51. [PDF]

Cell Death Dis
Xiao D, Yao J, Yang X, Xie Y, Zhou X, Li D, Peng M, Wang W, Zou H, Yang X.   +9 more
europepmc   +1 more source

Homologous recombination deficiency and genomic alterations in advanced prostate cancer: insights for precision therapy. [PDF]

Oncologist
Mercinelli C, Pavlick D, Agarwal N, Spiess PE, Li R, Kamat AM, Grivas P, Gupta S, Maiorano BA, Tateo V, Cigliola A, Piacentini M, Jacob JM, Bratslavsky G, Basnet A, Ross JS, Necchi A.   +16 more
europepmc   +1 more source

<i>BRCA2</i> Reversion Mutation after Neoadjuvant Dose-Dense EC and Dose-Dense Paclitaxel in Triple-Negative Breast Cancer: A Case Report and Literature Review. [PDF]

Surg Case Rep
Hikino H, Otani A, Makino Y.
europepmc   +1 more source

BRCA1/2 and CHEK2 Pathogenic Variants in Urological Cancers: A Portuguese Single-Center Experience. [PDF]

Cureus
Quinto Pereira M, Miguel I, Fragoso S, Duarte T, Santos S, Rodrigues P, Pereira C, Vaz F.   +7 more
europepmc   +1 more source

Germline Pathogenic Variants in Homologous Recombination Pathway Genes Are Frequent in Pancreatobiliary Ampullary Carcinoma. [PDF]

JCO Precis Oncol
Misyura M, Selenica P, Ozcan K, Kemel Y, Basturk O, O'Reilly EM, Reis-Filho JS, Beets-Tan R, Stadler ZK, Weigelt B, Mandelker D.   +10 more
europepmc   +1 more source

Integrating breast tumour homologous recombination deficiency status to aid germline BRCA1 and BRCA2 variant classification. [PDF]

EBioMedicine
Fortuno C, Zhang J, Koufariotis LT, Hollway G, Wood S, Pearson JV, Simpson PT, Lakhani SR, McCart Reed AE, Thorne H, Mann GB, Skandarajah AR, Devereux L, Zhao Q, De Silva DL, Lindeman GJ, Waring P, James PA, Campbell I, Spurdle AB, Waddell N.   +20 more
europepmc   +1 more source

FOLFIRINOX vs. Gemcitabine/Nab-Paclitaxel for Pancreatic Cancer by BRCA2 and TMB Status: A Japanese C-CAT Database Study. [PDF]

Cancer Sci
Mizuno K, Ishikawa T, Ito T, Takano Y, Maeda O, Kawashima H, Ando Y.   +6 more
europepmc   +1 more source

Centralized Homologous Recombination Repair Testing in Metastatic Castration-Resistant Prostate Cancer: Real-World Data from a Multicenter Spanish Precision Oncology Program. [PDF]

Cancers (Basel)
Caramelo B, García-Berbel P, Carmen SD, Calapaqui A, Corrêa L, Martinez-Villaseñor L, Sotelo M, Rojo F, Gómez-Román J, Duran I, Freire J.   +10 more
europepmc   +1 more source

Correction: Cosegregation analysis following an excellent response to olaparib in a pancreatic cancer patient carrier of BRCA2:c.7892 T > C variant enables its reclassification from VUS to pathogenic. [PDF]

BJC Rep
Strojnik K, Blatnik A, Krajc M, Novaković A, Ignjatović M, Ocvirk J, Stegel V, Škerl P, Klančar G, Novaković S, Šetrajčič Dragoš V.   +10 more
europepmc   +1 more source