Results 131 to 140 of about 66,967 (213)

Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers

Journal of Gastroenterology and Hepatology, Volume 41, Issue 3, Page 895-913, March 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancers, typically diagnosed at an advanced stage due to its subtle and often absent early symptoms. Despite representing only 3% of new cancer cases, it is projected to become the second leading cause of cancer‐related deaths by 2030.
Muhammad Masroor Hussain, Sana Qammar, Ju‐Mei Wang, Ao‐Qiang Zhai, Fu‐yu Li, Hai‐jie Hu   +5 more
wiley   +1 more source

Protein–protein interactions of Fanconi anemia proteins FANCI, FANCD2 and BRCA2 [PDF]

Acta Crystallographica Section A Foundations and Advances, 2017
Mohd Quadir Siddiqui, Yogendra S. Rajpurohit, Hari S. Misra, Ashok K. Varma   +3 more
openaire   +1 more source

Welcome Pathogens: Transient Heat Dampens Immune Responses to Acibenzolar‐S‐Methyl in Apple Plants

Plant, Cell &Environment, Volume 49, Issue 3, Page 1229-1248, March 2026.
ABSTRACT Climate change affects plant‐pathogen interactions, with disease outcome varying depending on the pathosystem and environmental scenario. In Arabidopsis, a thermo‐sensitive module of salicylic acid (SA) signalling makes immunity vulnerable to heat.
Erwan Chavonet, Bao‐huynh Nguyen, Christelle Heintz, Raphaël Cournol, Jitka Široká, Ondřej Novák, Romain Larbat, Matthieu Gaucher, Marie‐Noëlle Brisset, Florent Pantin, Alexandre Degrave   +10 more
wiley   +1 more source

Aumolertinib with carboplatin–pemetrexed versus aumolertinib for nonsmall cell lung cancer with EGFR and concomitant tumor suppressor genes (ACROSS2): An open‐label, multicenter, randomized phase 3 study

CA: A Cancer Journal for Clinicians, Volume 76, Issue 2, March/April 2026.
ABSTRACT Third‐generation epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR‐TKIs) are standard first‐line therapy for advanced, EGFR‐mutated nonsmall cell lung cancer (NSCLC). However, their benefit is limited in patients who have co‐existing tumor suppressor gene (TSG) mutations, highlighting a need for intensified strategies to ...
Jian‐Chun Duan, Jia Zhong, Bo‐Yang Sun, Wen‐Hua Zhao, Lin Wu, Kai‐Lun Fei, Qian Chu, Qi‐Sen Guo, Qi‐Bin Song, Yan Yu, Da‐Xing Zhu, Xin‐Yan Liu, Jun Zhao, Zhi‐Xiang Zhan, Shi Li, Lei Nie, Jie Lin, Xiao‐Dong Peng, Dian‐Sheng Zhong, Jin Zhou, Li‐Hua Li, Yun‐Fang Chen, Chen Hu, Tony Mok, Zhi‐Jie Wang, Jie Wang   +25 more
wiley   +1 more source

Rapid and sensitive detection of BRCA1/2 mutations in a diagnostic setting: Comparison of two high-resolution melting platforms [PDF]

, 2008
Claes, Kathleen, Coene, Ilse, De Leeneer, Kim, De Paepe, Anne, Poppe, Bruce   +4 more
core   +1 more source

<i>BRCA2</i> Reversion Mutation after Neoadjuvant Dose-Dense EC and Dose-Dense Paclitaxel in Triple-Negative Breast Cancer: A Case Report and Literature Review. [PDF]

Surg Case Rep
Hikino H, Otani A, Makino Y.
europepmc   +1 more source

Breast cancer susceptibility gene 2 upregulation alleviated cardiac hypertrophy in angiotensin II-treated mice. [PDF]

Biochem Biophys Rep
Liu K, Gong XX, Li Y, Li MZ, Si C, Zhou L.   +5 more
europepmc   +1 more source

Identification of Genetic Variants Among Breast Cancer Patients and At-Risk Individuals: A Cohort Study in Sri Lanka. [PDF]

Breast Cancer (Auckl)
Yatawara L, Hewavithana B, Ramanayake AP, Wickramasinghe S, Amarasiri M.   +4 more
europepmc   +1 more source

Ovarian follicular density in women with BRCA1 and BRCA2 mutations: new insights into the negative impact on ovarian reserve. [PDF]

J Ovarian Res
Maletta M, Vicenti R, Forastiere C, Di Santo S, Doglioli M, Lenzi J, Raffone A, Cobellis L, Perandini A, Somigliana E, Seracchioli R, Raimondo D.   +11 more
europepmc   +1 more source

Production of recombinant human BRCA2 encoded proteins in Ecoli

, 1997
Ankara : The Department of Molecular Biology and Genetics and Institute of Engineering and Science, Bilkent Univ., 1997. Thesis (Master's) -- Bilkent University, 1997. Includes bibliographical references leaves 98-109. Breast cancer is known to be the most common cancer among women in the world.
openaire   +1 more source