Results 171 to 180 of about 44,419 (235)

BRCA1 and BRCA2 pathogenic variants increase the risk of four less common cancer types. [PDF]

ESMO Open
Sasagawa H, Endo M, Iwasaki Y, Usui Y, Koyanagi YN, Innella G, Hadler J, Parsons MT, Numakura K, Kamatani Y, Murakami Y, Matsuo K, Matsuda K, Spurdle AB, Habuchi T, Momozawa Y.   +15 more
europepmc   +1 more source

Causative Role for a BRCA2 Germline Pathogenic Variant in External Auditory Canal Squamous Cell Carcinoma. [PDF]

Genes Chromosomes Cancer
Camacho-Valenzuela J, Pelletier D, Polak P, Fu L, Hamel N, Robles-Espinoza CD, Foulkes WD.   +6 more
europepmc   +1 more source

Exploring the somatic mutational landscape of ovarian cancer in Estonia. [PDF]

Acta Oncol
Tooming M, Rekker K, Toome K, Roht L, Laidre P, Fjodorova O, Šamarina U, Pajusalu S, Ilisson M, Peets P, Jõgi T, Klaup K, Ojamaa K, Niine-Roolaht EM, Kaarde P, Vettus E, Piirsoo J, Vahar H, Õunap K, Kahre T.   +19 more
europepmc   +1 more source

Prevalence of recurrent and non-recurrent BRCA1 and BRCA2 pathogenic variants in Polish breast cancer patients: insights from a regional genetic testing cohort from Lower Silesia. [PDF]

BMC Cancer
Matkowski R, Abrahamowska M, Michalowska D, Chrusciel A, Szelachowska J, Blomka D, Lawicka P, Czykalko E, Pietron A, Ekiert M, Doraczynska-Kowalik A, Janus-Szymanska G, Kasprzak P, Szynglarewicz B, Laczmanska I.   +14 more
europepmc   +1 more source

Contralateral breast cancer risks for BRCA1, BRCA2, PALB2, CHEK2, and ATM pathogenic variant carriers in two large cohort studies. [PDF]

BJC Rep
Allen I, Whish N, Yadav S, Boddicker NJ, Drukker C, van de Beek I, Eccles DM, Turnbull C, Pharoah P, Antoniou AC, Easton DF, Couch FJ, Schmidt MK, Tischkowitz M.   +13 more
europepmc   +1 more source

Correction: A comprehensive and accessible model for co-segregation analysis in BRCA1, BRCA2, and PALB2 variant classification. [PDF]

Hum Genet
Moghadasi S, Monajemi R, Braspenning ME, Vreeswijk MPG, Rodríguez-Girondo M.   +4 more
europepmc   +1 more source

Enhanced Detection of BRCA Copy Number Alterations Within a Commercial HRD Assay: Implications for Precision Oncology in Ovarian Cancer. [PDF]

Int J Mol Sci
De Bonis M, Iapicca P, De Paolis E, Brisighelli F, Evangelista J, Perrucci A, Ricciardi Tenore C, Maneri G, Concolino P, Piermattei A, Mozzetta I, Pasciuto T, Preziosi A, Giacò L, Duranti S, Nero C, Fagotti A, Minucci A.   +17 more
europepmc   +1 more source

Combining multiplexed assays of variant effect for enhanced BRCA2 variant classification. [PDF]

Nat Commun
Hu C, Sahu S, Chen W, Galloux M, Richardson ME, Bishop MF, Karam R, Pesaran T, Na J, Huang H, Weitzel JN, Nathanson KN, Yadav S, Boddicker NJ, Domchek SM, Monteiro AN, Iversen ES, Sharan SK, Couch FJ.   +18 more
europepmc   +1 more source

Exon-Specific Targeted Analysis of <i>BRCA1</i> and <i>BRCA2</i> Mutations in Bangladeshi Breast Cancer Patients. [PDF]

Cancer Inform
Dutta S, Rashid SMM, Islam S, Ahmed SF, Ayub M.   +4 more
europepmc   +1 more source

Comprehensive Investigation of a Novel Schiff Base: Synthesis, Anticancer Efficacy, Gene Expression Profiling, and Computational Analyses. [PDF]

Pharmaceuticals (Basel)
Agbektas T, Pazarcı Ö, Tas A, Huseynzada A, Guliyev R, Hasanova U, Buluz EC, Kaya S, Morales-Bayuelo A, Silig Y.   +9 more
europepmc   +1 more source