Results 201 to 210 of about 67,862 (241)

Invasive Lobular Carcinoma of the Male Breast With BRCA2 Mutation. [PDF]

Case Rep Pathol
Abe M, Saito F, Honma N, Tamaki Y, Goto M, Fukutake K, Sonobe S, Katagiri Y, Shibayama T, Ogata H.   +9 more
europepmc   +1 more source

Molecular characteristics and prognostic insights into BRCA-associated breast cancer in Kazakhstan. [PDF]

Sci Rep
Samigatova A, Altaeva N, Suleimenov Y, Sibiryakov P, Zhabagin K, Zhakypbekkyzy Z, Seksenbayev B, Yoshihiro N, Tsigengagel O.   +8 more
europepmc   +1 more source

Genetic Testing in Breast Cancer: Narrative Review and Clinical Insights. [PDF]

Maedica (Bucur)
Bistriceanu I, Ungureanu CO, Stoica RA, Giuglea C, Grigorean VT, Roca D, Mihaila R, Iordache N, Ginghina O.   +8 more
europepmc   +1 more source

Prevalence of <i>BRCA1</i> and <i>BRCA2</i> Germline Mutations in Vietnamese Patients With Triple-Negative Breast Cancer. [PDF]

Cancer Control
Toan TT, To TV, Lan TTH, Thinh NV, Anh DTN, Hanh BTM.   +5 more
europepmc   +1 more source

Sequential platinum and PARP Inhibition enhances PD1 immunotherapy efficacy in murine Brca2 mutated pancreatic cancer. [PDF]

Sci Rep
McVey JC, Wattenberg MM, Coho H, Infante K, Markowitz K, Delman D, Clendenin C, Furth EE, Tondon R, Stanger BZ, Vonderheide RH, Reiss KA, Beatty GL.   +12 more
europepmc   +1 more source

Genomic landscape and clinical impact of BRCA1/2 pathogenic variants in metastatic castration-resistant prostate cancer. [PDF]

NPJ Precis Oncol
Iida K, Urabe F, Matsui Y, Tashiro K, Yoshihara K, Urabe Y, Ishikawa T, Matsuzaki J, Kimura T, Saito Y.   +9 more
europepmc   +1 more source

A novel BRCA mutation classification system reveals differential responses to PARP inhibition and prognostic outcomes in epithelial ovarian cancer: a multicenter study. [PDF]

ESMO Open
Liu Q, Fan Y, Huang C, Wu M, Jin Y, Tao L, Liu Y, Song J, Wang S, Kong W, Huang X, Ha C, Cui Z, Zhao D, Yang X, Qiao J, Zhang Y, Li Y, Guo H.   +18 more
europepmc   +1 more source

Deoxycytidine kinase inhibition: Rewiring tumor nucleotide metabolism for therapeutic gain. [PDF]

Nucleosides Nucleotides Nucleic Acids
Clark PM, Thompson CB, Schultz KA.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Suppression of polyploidy by the BRCA2 protein

Cancer Letters, 2007
Mounting evidence implicates BRCA2 not only in maintenance of genome integrity but also in cell-cycle checkpoints. However, the contribution of BRCA2 in the checkpoints is still far from being understood. Here, we demonstrate that breast cancer cells MX-1 are unable to maintain genome integrity, which results in gross polyploidization.
Sagulenko, Evgeny, Savelyeva, Larissa, Ehemann, Volker, Sagulenko, Vitaliya, Hofmann, Wera, Arnold, Katrin, Claas, Andreas, Scherneck, Siegfried, Schwab, Manfred   +8 more
openaire   +3 more sources

Nuclear Localization Signals of the BRCA2 Protein

Biochemical and Biophysical Research Communications, 2000
BRCA2 is a tumor suppressor gene whose germline mutations increase the lifetime risk of breast cancer. BRCA2 encodes a large nuclear protein involved in DNA repair, but the location of its functional domain has been unclear. Here, we report nuclear localization signals (NLSs) of the BRCA2 protein.
K, Yano, K, Morotomi, H, Saito, M, Kato, F, Matsuo, Y, Miki   +5 more
openaire   +2 more sources