Results 221 to 230 of about 67,862 (241)
Some of the next articles are maybe not open access.
The Brca1 and Brca2 proteins and tumor pathogenesis.
Anticancer research, 2000Germline alterations of the BRCA1 or BRCA2 genes result in susceptibility to breast and ovarian cancer. Protein-protein interaction studies, transcription activity and mouse knockout experiments have suggested that the Brca1 and Brca2 proteins are of importance in DNA repair and maintenance of genome integrity, possibly due to the transactivation ...
openaire +1 more source
Internal repeats in the BRCA2 protein sequence
Nature Genetics, 1996Peer Bork +2 more
openaire +1 more source
Nuclear location and cell cycle regulation of the BRCA2 protein.
Cancer research, 1998Women carrying a germ-line mutation in the BRCA1 or BRCA2 genes have a high risk of developing breast cancer, and loss of the wild-type allele in tumors suggests that these genes function as tumor suppressor genes. The BRCA2 gene encodes a 3418-amino acid protein with no significant sequence similarity to any known protein.
D, Bertwistle +7 more
openaire +1 more source
Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
Nature, 1997Shyam K Sharan +2 more
exaly
BRCA1 and BRCA2: different roles in a common pathway of genome protection
Nature Reviews Cancer, 2011Simon N Powell
exaly
Presymptomatic DNA testing and prophylactic surgery in families with a BRCA1 or BRCA2 mutation
Lancet, The, 2000Maaike P G Vreeswijk
exaly