Results 141 to 150 of about 5,434 (195)

Multi-Omics Mendelian Randomization Identifies Therapeutic Targets for Sjögren's Disease with Clinical and Bayesian Validation. [PDF]

J Inflamm Res
He J, Li K, Guo Z, Zhou X, Tang X.
europepmc   +1 more source

In-Cell Approach to Evaluate E3 Ligases for Use in Targeted Protein Degradation. [PDF]

J Am Chem Soc
Zheng Y, Singh A, Niu Z, Marin V, Young J, Richardson P, Hemshorn ML, Cooley RB, Karplus PA, Puvar K, Warder SE, Vasudevan A, Reitsma JM, Mehl RA.   +13 more
europepmc   +1 more source

CAND1 and CAND2 drive CUL4 substrate receptor exchange with largely comparable biochemical efficiency, unlike their relative effects on CUL1. [PDF]

Structure
Wang K, Kenny S, Chagan Z, Li L, Das C, Liu X.   +5 more
europepmc   +1 more source

Integrating plasma proteomics and genome-wide association data to identify therapeutic targets for retinal neurodegenerative diseases in Europeans. [PDF]

Int J Ophthalmol
Guo YJ, Chen ZQ, Zhao J.
europepmc   +1 more source

Correction of the molecular phenotype of X-linked Dystonia-Parkinsonism reveals a non-canonical function of BRD4. [PDF]

Nat Commun
Capponi S, Ehret S, Camgöz Z, Gather F, Vaine CA, Özyerli-Göknar E, Follo M, Bragg DC, Vogel T, Timmers HTM.   +9 more
europepmc   +1 more source

A new 4-atom linker enables PROTAC development and imaging. [PDF]

RSC Chem Biol
Letsios S, Carrasco G, Lee M, Wagiet M, Madureira M, Samways M, Khan Z, Brunton VG, Grubisha O, Hulme AN.   +9 more
europepmc   +1 more source

Epigenetic suppression of synovial inflammation and osteoclast differentiation in rheumatoid arthritis by I-BET762. [PDF]

Sci Rep
Kim RH, Choi SU, Song YW.
europepmc   +1 more source

OsBIR3 maintains the homeostasis of OsBRI1, OsREM4.1, and Brd2 protein levels in brassinosteroid pathways in rice. [PDF]

Plant Biotechnol J
Guo J, Zhang H, Fan M, Xiao Y, Zhu Y, Chen C, Shu H, Wei M, Luo Y, Yang X, Liu Y, Xu J, Zhao K, Wang S, Yang B, Sun C, Deng X, Wang P.   +17 more
europepmc   +1 more source

Proteome-Wide Discovery of Degradable Proteins Using Bifunctional Molecules. [PDF]

ACS Cent Sci
Forrest I, Conway LP, Gathmann C, Jadhav AM, Chiu TY, Chaheine CM, Estrada M, Shrestha A, Sarris K, Reitsma JM, Warder SE, Vasudevan A, McLoughlin SM, Parker CG.   +13 more
europepmc   +1 more source