Results 151 to 160 of about 26,367 (213)

Cbx4 SUMOylates BRD4 to regulate the expression of inflammatory cytokines in post-traumatic osteoarthritis

Experimental and Molecular Medicine
Brominated domain protein 4 (BRD4) is a chromatin reader known to exacerbate the inflammatory response in post-traumatic osteoarthritis (PTOA) by controlling the expression of inflammatory cytokines. However, the extent to which this regulatory effect is
Ding Zhou, Jia-Ming Tian, Zi Li, Jun Huang   +3 more
doaj   +1 more source

Novel Bromodomain BRD4 Inhibitors for Treating Cancer [PDF]

ACS Medicinal Chemistry Letters, 2021
openaire   +2 more sources

High-intensity interval training alleviates COPD-induced gastrocnemius muscle dysfunction via the BRD4/PGC-1α axis through restoring mitochondrial function and oxidative fiber composition. [PDF]

J Muscle Res Cell Motil
Zhu C, Peng W, Yang L, Zhang W.
europepmc   +1 more source

Protocol for immunofluorescence detection and quantitative analysis of pH-dependent transcriptional condensates. [PDF]

STAR Protoc
Wu Z, Raghunathan K, Zhong Z, Thiagarajah J, Zhou X.   +4 more
europepmc   +1 more source

Bromodomain-containing protein 4 in inflammatory diseases: molecular mechanisms and therapeutic potential. [PDF]

J Inflamm (Lond)
Frascatani R, Marafini I, Colella M, Monteleone G.   +3 more
europepmc   +1 more source

Nutrient-driven histone acetylation underlies energy storage and mobilization. [PDF]

Mol Metab
Chen L, Zhu L, Xiao H, Wang X, Xia F, Wang Z, Wu L, Wu D, Liu Q, Cheng J, Qi J, Duan Q.   +11 more
europepmc   +1 more source

Bivalent BRD4 Inhibitor AZD5153 [PDF]

, 2020
openaire   +1 more source

Bitter gourd peptides (BG) alleviate lupus progression in mice through regulation of miR-146a/BRD4 axis in macrophages. [PDF]

Front Immunol
Wu Y, Han W, Li X, Su X.
europepmc   +1 more source

SHP2 improved Late-onset fetal growth restriction via modulating ROS/BRD4/PI3K/YAP/PIGF signaling induced angiogenesis. [PDF]

PLoS One
Li F, Li Y, Hao W, Zhang X, Shen X, Yang B, Zhang W, Fu L, Gu S.   +8 more
europepmc   +1 more source

Development of PolyHis-Targeting PROTAC Degraders. [PDF]

Angew Chem Int Ed Engl
Chen H, Zhu D, Billitti M, Sun A, Jin L, Moser E, Mivechi NF, Zheng G, Lv D.   +8 more
europepmc   +1 more source