Results 61 to 70 of about 1,835,670 (328)

Deep Neural Network Using Transfer Learning Technique for MOSFETs With Different Gate Lengths in Avalanche Region

IEEE Access
In this paper, a transfer learning technique was first utilized to obtain deep neural network models for different gate lengths in the avalanche breakdown regime. Once the characteristics of a gate-length metal-oxide-semiconductor field-effect transistor
Chie-In Lee, Shi-Yan Zhang, Shih-Chieh Li, Jia-Han Yang, Jian Cheng Su   +4 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Experimental Study on the Discharge Characteristics of a Dripping ‘Rod–Plane’ Air Gap at High Altitude Under DC Voltages

Energies
High-voltage transmission and substation projects at high altitudes are pivotal in realizing the objective of universal electricity access. However, the reduced air density at elevated heights facilitates the formation and propagation of discharges ...
Chuyan Zhang, Xi Wang, Xinzhe Yu, Kaixuan Qu, Yuxi Dong, Yu Deng   +5 more
doaj   +1 more source

Rashba induced chirality switching of domain walls and suppression of the Walker breakdown

, 2014
In conventional domain wall systems the aim of a high domain wall velocity may be hindered by the occurrence of a Walker breakdown at comparably low current density.
Creutzburg, Marcus, Stier, Martin, Thorwart, Michael   +2 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Modeling and optimization of the multichannel spark discharge [PDF]

, 2017
This paper reports a novel analytic model of this multichannel spark discharge, considering the delay time in the breakdown process, the electric transforming of the discharge channel from a capacitor to a resistor induced by the air breakdown, and the ...
Jia, M., Li, Y-H., Song, H-M., Sun, Z., Wu, Y., Zhang, Z-B.   +5 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Ehrenfest breakdown of the mean-field dynamics of Bose gases

, 2016
The mean-field dynamics of a Bose gas is shown to break down at time $\tau_h = (c_1/\gamma) \ln N$ where $\gamma$ is the Lyapunov exponent of the mean-field theory, $N$ is the number of bosons, and $c_1$ is a system-dependent constant. The breakdown time
Han, Xizhi, Wu, Biao
core   +1 more source

Only the strong survive: therapeutic selective pressure drives medulloblastoma leptomeningeal metastasis

Molecular Oncology, EarlyView.
Radiation therapy induces cancer cell death and immune cell infiltration, mainly monocytes, macrophages, and dendritic cells. Elevated serum cytokine levels and disruption of the blood–brain barrier promote leptomeningeal dissemination. Cotreatment with dexamethasone reduces cytokine levels, preserves barrier integrity, and limits metastatic spread ...
Francis Y. He, Adrienne Boire
wiley   +1 more source