Results 61 to 70 of about 1,910,109 (318)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Model-Independent Analysis of Soft Terms in Effective Supergravity and in String Theory

, 1993
We discuss supersymmetry breakdown in effective supergravities such as emerge in the low-energy limit of superstring theory. Without specifying the precise trigger of the breakdown, we analyse the soft parameters in the Lagrangian of the supersymmetrized
Amati, Antoniadis, Antoniadis, Barbieri, Barieri, Binétruy, Cardoso Lopes, Casas, Chun, Cremmer, Cvetč, Derendinger, Derendinger, Dine, Dixon, Dixon, Dixon, Ellis, Ferrara, Font, Girardello, Giudice, Ibáñez, Jan Louis, Kim, Krasnikov, Louis, Louis, Nilles, Nilles, Nilles, Nilles, Shifman, Shifman, Soni, Taylor, Vadim S. Kaplunovsky   +36 more
core   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Rashba induced chirality switching of domain walls and suppression of the Walker breakdown

, 2014
In conventional domain wall systems the aim of a high domain wall velocity may be hindered by the occurrence of a Walker breakdown at comparably low current density.
Creutzburg, Marcus, Stier, Martin, Thorwart, Michael   +2 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Impact of Electrode Distance in a Quasi-Uniform Model Electrode System on Lightning Impulse Breakdown Voltage in Various Insulating Liquids

Energies
This study presents findings on the influence of gap length distance on the lightning impulse breakdown voltage of three dielectric liquids of different chemical origins.
Wiktor Kunikowski, Pawel Rozga, Bartlomiej Pasternak, Jakub Staniewski, Filip Stuchala, Konrad Strzelecki   +5 more
doaj   +1 more source

Analysis of single server repairable queueing system with many kinds of service, single working vacation and standby server [PDF]

Yugoslav Journal of Operations Research
We consider a single server queueing model in which the customers arrive according to a Markovian Arrival Process (MAP). We modeled this queueing system with many kinds of service where the customers can choose any kind from the server.
Baby Saroja K., Suvitha V.
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Modern theory of magnetic breakdown

, 2017
The modern semiclassical theory of a Bloch electron in a magnetic field encompasses the orbital magnetization and geometric phase. Beyond this semiclassical theory lies the quantum description of field-induced tunneling between semiclassical orbits ...
Alexandradinata, A., Glazman, Leonid
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source