Results 171 to 180 of about 2,528,262 (264)

Macrophage-Derived CuET Vesicles Synergistically Enhance Paclitaxel Efficacy by Inhibiting Tumor Growth and Boosting Immunity in Breast Cancer

open access: yesInternational Journal of Nanomedicine
Xiaoling Guo,1,* Lina Zhou,2,3,* Anya Buerliesi,1,* Jiahui Ye,1 Yinhua Lv,1,3 Wenqian Wei,1,3 Jinlan Jiao,1 Weihong Ge,2– 4 Yun Zhu,2– 4 Weijie Zhang1,3 1Division of Breast Surgery, Department of General Surgery, Nanjing Drum ...
Guo X   +9 more
doaj  

Evaluation of Surgeons' Perspectives and Perceived Readiness to Adopt Minimally Invasive Breast Surgery in a Low- and Middle-Income Setting. [PDF]

open access: yesWorld J Surg
Baderiya D   +13 more
europepmc   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin   +17 more
wiley   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

Endoscopic and Robotic Minimally Invasive Breast Surgery (MIBS) for Benign Breast Lesions: Our Experience of 80 Cases and Descriptive Comparison. [PDF]

open access: yesEur J Breast Health
Ramesh RS   +6 more
europepmc   +1 more source

F7 Drives Gastric Cancer Metastasis Through Anoikis Resistance and Tumor Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Coagulation factor VII (F7) has been implicated in tumor progression; however, its role in gastric cancer metastasis and immune evasion remains incompletely understood. In this study, we identified F7 as a clinically relevant driver of gastric cancer.
Lei Gao   +9 more
wiley   +1 more source

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