Results 91 to 100 of about 22,173 (305)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Materials for Fusion Applications [PDF]
, 2017 An overview of materials foreseen for use or already used in fusion devices is given. The operating conditions, material requirements and characteristics of candidate materials in several specific application segments are briefly reviewed. These include:
Matějíček , Jiří
core
SFR with once-through depleted uranium breed & burn blanket
Progress in Nuclear Energy, 2015 This paper assesses the feasibility of Sodium-cooled Fast Reactor (SFR) cores that have TRU recycled seeds and once-through depleted uranium blankets. The design objective of these Seed-and-Blanket (SB the blanket batches are gradually shuffled inward, while one third of the fuel batches in the seed are recycled.
Zhang, Guanheng +3 more
openaire +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
An assessment of internal blankets for gas-cooled fast reactors [PDF]
, 1980 Originally presented as first author's thesis (Ph. D.--Massachusetts Institute of Technology), 1980Includes bibliographical references (pages 338-346)Sponsored by General Atomic ...
Driscoll, M. J., Lancaster, Dale Burkham
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Nuclear Materials and EnergyThe control of tritium (3H) in liquid-based tritium breeding blankets (TBBs) is one of the key points to assure their correct performance to prove the 3H sufficiency.
Antonio Hinojo +3 more
doaj +1 more source
, 1972 Statement of responsibility on title-page reads: editors: M.J. Driscoll, D.D. Lanning, I. Kaplan; contributors: S. T. Brewer, G.J. Brown, P. Delaquil, M.J. Driscoll, G.A. Ducat, I.A. Forbes, M. V. Gregory, S.Y. Ho, M.S. Kalra, C.S. Kang, L.T.
Brewer, Shelby Templeton +21 more
core
DEMO Breeding Blanket Concepts in EUROfusion work package breeding blanket (WPBB)
, 2021 Zhou, Guangming +1 more
openaire +3 more sources