Results 91 to 100 of about 1,329 (294)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

A novel solution for hydrogen monitoring in fusion processes: 3D printed BaCe0.6Zr0.3Y0.1O3-α sensors

open access: yesNuclear Materials and Energy
The control of tritium (3H) in liquid-based tritium breeding blankets (TBBs) is one of the key points to assure their correct performance to prove the 3H sufficiency.
Antonio Hinojo   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Optimization of tritium breeding in (D,T) fusion driver hybrid blankets [PDF]

open access: yes, 2001
Fen Bilimleri Enstitüsü, Makine Mühendisliği Ana Bilim DalıÖZET (D,T) FÜZYON SÜRÜCÜLÜ HİBRİD BLANKETDE TRİTYUM ÜRETİMİNİN OPTİMİZ ASYONU KAYA, Ahmet Niğde Üniversitesi Fen Bilimleri Enstitüsü Makine Mühendisliği Anabilim Dalı Danışman: Prof. Dr.
Kaya, Ahmet
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

High performance ceramic coating for DEMO Breeding Blankets

open access: yes, 2017
This Ph.D work focuses the characterization of alumina (Al2O3) ceramic coating as barrier against hydrogen permeation and corrosion in heavy liquid metals as well as the development of custom made Atomic Layer Deposition facility.
IADICICCO, DANIELE
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Analysis of a segmentation approach to breeder blanket design and the utilisation of FLiBe as a novel neutron reflector

open access: yesNuclear Fusion
Tritium production in a fusion reactor is essential for a deuterium-tritium burning plasma source, and designing a lithium-containing breeder blanket is crucial for a closed fuel cycle in an electricity-to-grid power plant.
Adam J. Barker   +2 more
doaj   +1 more source

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