Results 21 to 30 of about 735 (162)

Brevetoxin Metabolites: Emerging Toxins in French Shellfish Determined by LC-MS/MS and ELISA

Marine Drugs
In France, as part of the monitoring program for the emergence of marine toxins in shellfish (EMERGTOX), brevetoxins (BTX-2, BTX-3) were first detected in shellfish from Corsica (Mediterranean Sea) in 2018.
Zouher Amzil, Amélie Derrien, Korian Lhaute, Aouregan Terre Terrillon, Simon Tanniou   +4 more
doaj   +2 more sources

Effects of in vitro Brevetoxin Exposure on Apoptosis and Cellular Metabolism in a Leukemic T Cell Line (Jurkat)

Marine Drugs, 2008
Harmful algal blooms (HABs) of the toxic dinoflagellate, Karenia brevis, produce red tide toxins, or brevetoxins. Significant health effects associated with red tide toxin exposure have been reported in sea life and in humans, with brevetoxins documented
Catherine Walsh, John Sleasman, Richard Pierce   +2 more
exaly   +2 more sources

Immune Modulating Brevetoxins: Monocyte Cytotoxicity, Apoptosis, and Activation of M1/M2 Response Elements Is Dependent on Reactive Groups

Marine Drugs, 2022
Brevetoxins are a suite of marine neurotoxins that activate voltage-gated sodium channels (VGSCs) in cell membranes, with toxicity occurring from persistent activation of the channel at high doses.
Jennifer R. McCall, Kathryn T. Sausman, Devon M. Keeler, Ariel P. Brown, Stephanie L. Turrise   +4 more
doaj   +1 more source

Development of a New Monoclonal Antibody against Brevetoxins in Oyster Samples Based on the Indirect Competitive Enzyme-Linked Immunosorbent Assay

Foods, 2021
The consumption of shellfish contaminated with brevetoxins, a family of ladder-frame polyether toxins formed during blooms of the marine dinoflagellate Karenia brevis, can cause neurotoxic poisoning, leading to gastroenteritis and neurotoxic effects.
Xiya Zhang, Mingyue Ding, Chensi Zhang, Yexuan Mao, Youyi Wang, Peipei Li, Haiyang Jiang, Zhanhui Wang, Xuezhi Yu   +8 more
doaj   +1 more source

Guidance Level for Brevetoxins in French Shellfish [PDF]

Marine Drugs, 2021
Brevetoxins (BTXs) are marine biotoxins responsible for neurotoxic shellfish poisoning (NSP) after ingestion of contaminated shellfish. NSP is characterized by neurological, gastrointestinal and/or cardiovascular symptoms. The main known producer of BTXs is the dinoflagellate Karenia brevis, but other microalgae are also suspected to synthesize BTX ...
Arnich, Nathalie, Abadie, Eric, Amzil, Zouher, Dechraoui Bottein, Marie-Yasmine, Comte, Katia, Chaix, Estelle, Delcourt, Nicolas, Hort, Vincent, Mattei, César, Molgó, Jordi, Le Garrec, Raphaele   +10 more
openaire   +6 more sources

Detection of Brevetoxin in Human Plasma by ELISA [PDF]

Journal of Analytical Toxicology, 2021
Abstract Florida red tides have become more common and persistent in and around the Gulf of Mexico. When in bloom, red tides can produce brevetoxins in high concentrations, leading to human exposures primarily through contaminated food and ocean spray.
Brady R Cunningham, Rebecca M Coleman, Adam M Schaefer, Elizabeth I Hamelin, Rudolph C Johnson   +4 more
openaire   +2 more sources

Total Synthesis of Brevetoxin-B [PDF]

Journal of the American Chemical Society, 2003
Brevetoxin-B (BTX-B), produced by the red tide organism, Gymnodium breve Davis, is the first member of marine polycyclic ethers to be structurally elucidated and one of the most potent neurotoxins. The structural feature is a trans-fused polycyclic ether ring system with 23 stereocenters.
Goh, Matsuo, Koji, Kawamura, Nobuyuki, Hori, Hiroko, Matsukura, Tadashi, Nakata   +4 more
openaire   +2 more sources

Utility of Red Tide (Karenia brevis) Monitoring Data as a Predictive Tool to Estimate Brevetoxin Accumulation in Live, Free-Ranging Marine Mammals

Frontiers in Marine Science, 2021
Exposure of common bottlenose dolphins (Tursiops truncatus) to brevetoxins (PbTx) produced by blooms of the toxic phytoplankton Karenia brevis frequently results in severe health impacts, including illness and large-scale mortality events.
Spencer E. Fire, Glenn A. Miller, Edna R. Sabater, Randall S. Wells   +3 more
doaj   +1 more source

Exposure to the Florida red tide dinoflagellate, Karenia brevis, and its associated brevetoxins induces ecophysiological and proteomic alterations in Porites astreoides. [PDF]

PLoS ONE, 2020
As reef-building corals are increasingly being exposed to persistent threats that operate on both regional and global scales, there is a pressing need to better understand the complex processes that diminish coral populations. This study investigated the
David A Reynolds, Mi-Jeong Yoo, Danielle L Dixson, Cliff Ross   +3 more
doaj   +1 more source

Pacific-Ciguatoxin-2 and Brevetoxin-1 Induce the Sensitization of Sensory Receptors Mediating Pain and Pruritus in Sensory Neurons

Marine Drugs, 2021
Ciguatera fish poisoning (CFP) and neurotoxic shellfish poisoning syndromes are induced by the consumption of seafood contaminated by ciguatoxins and brevetoxins.
Ophélie Pierre, Maxime Fouchard, Nelig Le Goux, Paul Buscaglia, Raphaël Leschiera, Richard J. Lewis, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +9 more
doaj   +1 more source