Results 31 to 40 of about 735 (162)
Marine Drugs, 2021 The recently characterized single-domain voltage-gated ion channels from eukaryotic protists (EukCats) provide an array of novel channel proteins upon which to test the pharmacology of both clinically and environmentally relevant marine toxins.
Ping Yates +2 more
doaj +1 more source
Chemistry – A European Journal, Volume 29, Issue 72, December 22, 2023., 2023 The fully functionalized A−F ring system of the Pacific ciguatoxin CTX3C suitable for coupling to the I−M fragment of the natural product, has been synthesized from a simple glucal derivative. A six‐step sequence that features ring‐closing metathesis and stereoselective palladium‐mediated allylation has been deployed in an iterative manner to construct
Myron Triantafyllakis +4 more
wiley +1 more source
First Light Demonstration of Red Solar Induced Fluorescence for Harmful Algal Bloom Monitoring
Geophysical Research Letters, Volume 50, Issue 13, 16 July 2023., 2023 Abstract The risks harmful algal blooms (HAB) pose to aquatic ecosystems, public health, and coastal economies necessitate supplementation of current observation strategies. Herein, we explore the use of red solar induced fluorescence (SIF) from the TROPOspheric Monitoring Instrument (TROPOMI), a remote sensing measurement retrievable in variable cloud
Kelly Luis +3 more
wiley +1 more source
PLoS ONE, 2011 Sentinel species such as bottlenose dolphins (Tursiops truncatus) can be impacted by large-scale mortality events due to exposure to marine algal toxins.
Michael J Twiner +9 more
doaj +1 more source
Brevetoxin versus Brevenal Modulation of Human Nav1 Channels
Marine Drugs, 2023 Brevetoxins (PbTx) and brevenal are marine ladder-frame polyethers. PbTx binds to and activates voltage-gated sodium (Nav) channels in native tissues, whereas brevenal antagonizes these actions.
Rocio K. Finol-Urdaneta +3 more
doaj +1 more source
Cells, 2020 Red tides involving Karenia brevis expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory syndrome and sensory disturbances.
Ophélie Pierre +8 more
doaj +1 more source
Toxins, 2022 The harmful algal bloom species, Karenia brevis, forms annual, often intense blooms in the Gulf of Mexico, particularly along the west Florida shelf. Though the ability of K.
Richard Wayne Litaker +5 more
doaj +1 more source
Structure Activity Relationship of Brevenal Hydrazide Derivatives
Marine Drugs, 2014 Brevenal is a ladder frame polyether produced by the dinoflagellate Karenia brevis. This organism is also responsible for the production of the neurotoxic compounds known as brevetoxins. Ingestion or inhalation of the brevetoxins leads to adverse effects
Allan Goodman +6 more
doaj +1 more source
Acute Effects of Brevetoxin-3 Administered via Oral Gavage to Mice
Marine Drugs, 2023 Brevetoxins (BTXs) constitute a family of lipid-soluble toxic cyclic polyethers mainly produced by Karenia brevis, which is the main vector for a foodborne syndrome known as neurotoxic shellfish poisoning (NSP) in humans.
Peggy Barbe +6 more
doaj +1 more source
Synthesis, Modeling, and Biological Evaluation of Analogues of the Semisynthetic Brevetoxin Antagonist β‐Naphthoyl‐Brevetoxin [PDF]
ChemBioChem, 2007 AbstractBrevetoxins are neurotoxic compounds produced by the dinoflagellate Karenia brevis. Extensive blooms induce neurotoxic shellfish poisoning (NSP) and asthma‐like symptoms in humans. β‐naphthoyl‐brevetoxin, the first semisynthetic brevetoxin antagonist, has been defined as the lead compound in the investigation of the mechanisms of ...
Sophie, Michelliza +4 more
openaire +2 more sources