Results 1 to 10 of about 8,176 (221)

Brimonidine as a possible treatment for myopia [PDF]

BMC Ophthalmology
Background Myopia is becoming a huge burden on the world’s public health systems. The purpose of this study was to explore the effect of brimonidine in the treatment of form-deprivation myopia (FDM) and the relationship between intraocular pressure (IOP)
Zixuan Peng, Aiqun Xiang, Hong He, Yaqi Luo, Shunliang Wu, Yanting Luo, Junming Yang, Ke Nie, Xingwu Zhong   +8 more
doaj   +4 more sources

Brimonidine is Neuroprotective in Animal Paradigm of Retinal Ganglion Cell Damage [PDF]

Frontiers in Pharmacology, 2021
To investigate the neuroprotective effect of brimonidine after retinal ischemia damage on mouse eye. Glaucoma is an optic neuropathy characterized by retinal ganglion cells (RGCs) death, irreversible peripheral and central visual field loss, and high ...
Federica Conti, Giovanni Luca Romano, Chiara Maria Eandi, Mario Damiano Toro, Mario Damiano Toro, Robert Rejdak, Giulia Di Benedetto, Francesca Lazzara, Renato Bernardini, Filippo Drago, Giuseppina Cantarella, Claudio Bucolo   +11 more
doaj   +6 more sources

A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model. [PDF]

PLoS ONE
Glaucoma is a multifactorial optic neuropathy that primarily affecting retinal ganglion cells (RGC). Brimonidine is an intraocular pressure-lowering drug with reported neuroprotective properties. This study aimed to compare the neuroprotective effects of
Ruta Maciulaitiene, Giedrius Kalesnykas, Dainius Haroldas Pauza, Ingrida Januleviciene   +3 more
doaj   +2 more sources

Ocular and Systemic Pharmacokinetics of Brimonidine and Timolol After Topical Administration in Rabbits: Comparison Between Fixed-Combination and Single Drugs [PDF]

Ophthalmology and Therapy, 2020
Introduction This study was aimed to compare ocular tissue distribution and systemic exposure of brimonidine and timolol after single topical administration to rabbits of fixed-combination ophthalmic solution of 0.1% brimonidine tartrate and 0.5% timolol
Gen Suzuki, Eriko Kunikane, Keisuke Shinno, Seiko Kozai, Masaaki Kurata, Akio Kawamura   +5 more
doaj   +2 more sources

Prophylactic effect of brimonidine to minimize the incidence of subconjunctival hemorrhage in the early postoperative period after 23G pars plana vitrectomy [PDF]

Therapeutic Advances in Ophthalmology, 2021
Background: Several studies have investigated and demonstrated the prophylactic effect of brimonidine drops in preventing subconjunctival hemorrhage in some microincisional ophthalmic surgeries, such as intravitreal injections or cataract surgery ...
Mari Carmen Desco, Julio Cesar Molina Martín, Jorge Mataix-Boronat, Isabel Pascual-Camps, Elena Palacios-Pozo, Marisa Barón-García, David P Piñero, Amparo Navea-Tejerina   +7 more
doaj   +2 more sources

Effect of brimonidine tartrate on basophil activation in glaucoma patients

International Journal of Ophthalmology, 2020
AIM: To evaluate the mechanism of which brimonidine tartrate 0.15% causes clinical hypersensitivity. METHODS: A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to a control group consisting 13 ...
Eldar Rosenfeld, Dana Barequet, Gilad Rabina, Sheila Langier, Moshe Lazar, Gabi Shemesh, Shimon Kurtz, Shmuel Kivity   +7 more
doaj   +2 more sources

Efficacy of three different formulations of brimonidine for control of intraocular pressure in primary open-angle glaucoma: A 6-week randomized trial

Oman Journal of Ophthalmology, 2018
BACKGROUND: To compare the intraocular pressure (IOP)-lowering efficacy and safety of brimonidine (0.2%), brimonidine purite (0.15%), and brimonidine purite (0.1%) in patients of primary open-angle glaucoma (POAG).
Anubha Bhatti, Gursatinder Singh
doaj   +2 more sources

Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension [PDF]

Clinical Ophthalmology, 2008
Anna Galanopoulos1, Ivan Goldberg21Senior Visiting Ophthalmologist, South Australian Institute of Ophthalmology and Dept of Ophthalmology and Visual Sciences, University of Adelaide, South Australia; 2Clinical Associate Professor, University of Sydney ...
Anna Galanopoulos, Ivan Goldberg
doaj   +5 more sources

The efficacy and safety of add-on 0.1% brimonidine tartrate preserved with sodium chlorite in on-treatment Japanese normal-tension glaucoma patients

Clinical Ophthalmology, 2014
Toyoaki Tsumura,1 Keiji Yoshikawa,2 Tairo Kimura,3 Hirotaka Suzumura,4 Miwako Kawashima,5 Mami Nanno,6 Kiyotaka Ishijima,7 Ryuji Takeda8 1Fussa Hospital, Tokyo, Japan; 2Yoshikawa Eye Clinic, Tokyo, Japan; 3Ueno Eye Clinic, Tokyo, Japan; 4Suzumura Eye ...
Tsumura T, Yoshikawa K, Kimura T, Suzumura H, Kawashima M, Nanno M, Ishijima K, Takeda R   +7 more
doaj   +3 more sources

The Efficacy and Safety Associated with Switching from Concomitant Brimonidine and Ripasudil, or Brimonidine or Ripasudil Monotherapy to a Fixed Combination of Brimonidine and Ripasudil in Glaucoma Patients. [PDF]

J Clin Med
Objectives: The purpose of this study was to investigate switching from brimonidine and ripasudil, and brimonidine or ripasudil, to a fixed combination of brimonidine and ripasudil, and evaluate the associated efficacy and safety in glaucoma patients.
Onoe H, Hirooka K, Baba T, Nagayama M, Hirota A, Suzuki K, Sagara T, Mochizuki H, Kiuchi Y.   +8 more
europepmc   +3 more sources