Results 21 to 30 of about 8,852 (197)

Efficacy of three different formulations of brimonidine for control of intraocular pressure in primary open-angle glaucoma: A 6-week randomized trial

open access: yesOman Journal of Ophthalmology, 2018
BACKGROUND: To compare the intraocular pressure (IOP)-lowering efficacy and safety of brimonidine (0.2%), brimonidine purite (0.15%), and brimonidine purite (0.1%) in patients of primary open-angle glaucoma (POAG).
Anubha Bhatti, Gursatinder Singh
doaj   +1 more source

Rare diseases leading to childhood Glaucoma. epidemiology, pathophysiogenesis, and management [PDF]

open access: yes, 2015
Noteworthy heterogeneity exists in the rare diseases associated with childhood glaucoma. Primary congenital glaucoma is mostly sporadic; however, 10% to 40% of cases are familial. CYP1B1 gene mutations seem to account for 87% of familial cases and 27% of
Abdolrahimzadeh, Solmaz   +5 more
core   +3 more sources

Cationic supramolecular hydrogels for overcoming the skin barrier in drug delivery [PDF]

open access: yes, 2018
A cationic bis‐imidazolium‐based amphiphile was used to form thermoreversible nanostructured supramolecular hydrogels incorporating neutral and cationic drugs for the topical treatment of rosacea.
Amabilino, David B.   +6 more
core   +1 more source

Ocular and Systemic Pharmacokinetics of Brimonidine and Timolol After Topical Administration in Rabbits: Comparison Between Fixed-Combination and Single Drugs

open access: yesOphthalmology and Therapy, 2020
Introduction This study was aimed to compare ocular tissue distribution and systemic exposure of brimonidine and timolol after single topical administration to rabbits of fixed-combination ophthalmic solution of 0.1% brimonidine tartrate and 0.5% timolol
Gen Suzuki   +5 more
doaj   +1 more source

Evaluation of brimonidine-timolol fixed combination in patients of primary open-angle glaucoma

open access: yesIndian Journal of Ophthalmology, 2013
The aim of present study was to compare the efficacy and safety of fixed combination of brimonidine and timolol with individual components used as monotherapy in patients of primary open angle glaucoma.
Sachin R Joshi   +5 more
doaj   +1 more source

Safety, tolerability, and efficacy of fixed combination therapy with dorzolamide hydrochloride 2% and timolol maleate 0.5% in glaucoma and ocular hypertension. [PDF]

open access: yes, 2010
Glaucoma is a collection of diseases characterized by multifactorial progressive changes leading to visual field loss and optic neuropathy most frequently due to elevated intraocular pressure (IOP).
Bell, Nicholas P   +2 more
core   +3 more sources

Changes in visual function after intraocular pressure reduction using antiglaucoma medications [PDF]

open access: yes, 2009
Purpose To evaluate the change in visual function after starting glaucoma treatment and correlate this to a decrease in intraocular pressure (IOP) in primary open-angle glaucoma patients.Methods A prospective, randomized clinical trial was carried out ...
A Harris   +22 more
core   +2 more sources

24-h Efficacy of Glaucoma Treatment Options [PDF]

open access: yes, 2016
Current management of glaucoma entails the medical, laser, or surgical reduction of intraocular pressure (IOP) to a predetermined level of target IOP, which is commensurate with either stability or delayed progression of visual loss.
Banu, Bozkurt.   +8 more
core   +2 more sources

The acute and chronic effects of intravitreal anti-vascular endothelial growth factor injections on intraocular pressure: A review [PDF]

open access: yes, 2017
The acute and chronic effects of repeated intravitreal antivascular endothelial growth factor (VEGF) injections on intraocular pressure have not been fully characterized, and the development of sustained ocular hypertension could adversely affect ...
Bracha, Peter   +4 more
core   +1 more source

Where does selective laser trabeculoplasty stand now? A review [PDF]

open access: yes, 2016
Background: Chronic treatment of glaucoma can present a challenge in patients who lack the means and/or the discipline to use daily glaucoma medication. We wondered if selective laser trabeculoplasty (SLT) could be a useful alternative.
De Belder, Maya   +3 more
core   +2 more sources

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