Results 21 to 30 of about 10,864 (278)

Spotlight on brimonidine topical gel 0.33% for facial erythema of rosacea: safety, efficacy, and patient acceptability

open access: goldPatient Preference and Adherence, 2017
Michael S Anderson,1 Anish Nadkarni,1 Leah A Cardwell,1 Hossein Alinia,1 Steven R Feldman1–3 1Department of Dermatology, Center for Dermatology Research, 2Department of Pathology, 3Department of Public Health Sciences, Wake Forest School of ...
Anderson MS   +4 more
doaj   +3 more sources

Prolonged central nervous system and respiratory depression in preterm neonates after exposure to brimonidine tartrate and timolol maleate ophthalmic drops [PDF]

open access: greenGMS Ophthalmology Cases, 2020
Objective: We report three cases of preterm neonates who presented with central nervous system (CNS) and respiratory depression after inadvertent exposure to brimonidine tartrate 0.2% and timolol maleate 0.5% fixed-combination ophthalmic drops.Case ...
Azarcon, Corrina P., Santiago, Darby E.
doaj   +2 more sources

Is brimonidine ophthalmic a safe therapy for infants?

open access: goldJournal of Clinical Pharmacy and Therapeutics, 2006
Brimonidine is a topical alpha-2 agonist commonly used in the treatment of glaucoma. Brimonidine toxicity resembles that of clonidine overdose and is probably due to both imidazoline and alpha-2 adrenergic receptor effects. We report a case of a 6-week-old infant with congenital glaucoma who developed bradycardia and hypotension following the ...
G. Patrick Daubert
openalex   +4 more sources

The role of brimonidine tartrate gel in the treatment of rosacea

open access: greenClinical, Cosmetic and Investigational Dermatology, 2015
Rosacea is a chronic cutaneous condition with a prevalence rate ranging from 9.6% to 22% in recent studies. Facial erythema (transient and permanent) is considered a common denominator that is frequently observed in all subtypes of rosacea and is estimated to affect more than 40 million people worldwide.
Jackson JM   +4 more
openalex   +5 more sources

Effects of topical clonidine vs. brimonidine on choroidal blood flow and intraocular pressure during isometric exercise [PDF]

open access: hybrid, 2007
Günther Weigert   +4 more
core   +2 more sources

The potential of brimonidine for myopia treatment: Targeting MMP-2 to regulate choroidal thickness and control eye growth [PDF]

open access: yesHeliyon
Drug treatment studies are a focal point for identifying novel approaches to reduce myopia progression through basic science research. Here, we investigated the effects of various brimonidine administration routes and concentrations on form-deprivation ...
Aiqun Xiang   +8 more
doaj   +2 more sources

Preparation and Characterization of Ion-Sensitive Brimonidine Tartrate In Situ Gel for Ocular Delivery

open access: yesPharmaceuticals, 2023
Brimonidine tartrate (BRT) is a highly selective α2 adrenergic receptor agonist as treatment for patients with open angle glaucoma and high intraocular pressure.
Haonan Xu   +6 more
semanticscholar   +1 more source

Efficacy and safety of various brimonidine formulations in the treatment of glaucoma and ocular hypertension

open access: yesОфтальмохирургия, 2021
Purpose. To present data on the mechanism of action, efficacy, and side effects of various brimonidine dosage forms in the treatment of glaucoma and ocular hypertension.Material and methods. To perform the review, literature sources were searched through
A. V. Sidorova   +3 more
doaj   +1 more source

Preliminary evaluation of the efficacy and safety of brimonidine for general anesthesia

open access: yesBMC Anesthesiology, 2021
Background To determine the hypnotic and analgesic effects of brimonidine, and evaluate its efficacy and safety for general anesthesia. Potentiation of pentobarbital sleeping time following brimonidine administration was observed in mice, as was the ...
Chen Bin   +5 more
doaj   +1 more source

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

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