Results 61 to 70 of about 24,692 (192)

Respiratuvar depression after accidental nasal ingestion of brimonidine eye drops in infant

Turkish Journal of Emergency Medicine, 2016
Objectives: Brimonidine tartrate is an alpha-2 agonist used for glaucoma treatment. It can lead to serious poisoning symptoms when misused by children.
Ali Gunes, Hasan Balik, Servet Yel, Halil Kocamaz, Mehmet Bosnak   +4 more
doaj  

Novel Uses of Brimonidine

Delhi Journal of Ophthalmology
Brimonidine tartrate is a third-generation, highly selective alpha 2 agonist currently available in various formulations and doses to treat ophthalmological conditions. The aim of this article was to review pharmacokinetics, mechanisms, side effects, and
Hikkalagutti. S. Kruthika, Chauhan Tulika, Patyal Sagarika, Bhardwaj Kanika, Dabas Garvita   +4 more
doaj   +1 more source

FetoML: Interpretable predictions of the fetotoxicity of drugs based on machine learning approaches

Molecular Informatics, Volume 43, Issue 6, June 2024.
Abstract Pregnant females may use medications to manage health problems that develop during pregnancy or that they had prior to pregnancy. However, using medications during pregnancy has a potential risk to the fetus. Assessing the fetotoxicity of drugs is essential to ensure safe treatments, but the current process is challenged by ethical issues ...
Myeonghyeon Jeong, Sunyong Yoo
wiley   +1 more source

Nummular keratitis: A rare manifestation of brimonidine allergy

Oman Journal of Ophthalmology
A 32-year-old male, with juvenile open-angle glaucoma on chronic antiglaucoma therapy and recently introduced brimonidine eye drops to the treatment regimen, developed bilateral follicular conjunctivitis with subepithelial infiltrates (SEIs) initially ...
Maitha Al Asmi, Aisha Al Busaidi
doaj   +1 more source

A panoramic perspective of recent progress in 2D and 3D covalent organic frameworks for drug delivery

Aggregate, Volume 5, Issue 2, April 2024.
This review discusses covalent organic frameworks (COFs) as promising drug carriers for cancer treatment, emphasizing their advantageous structures and biocompatibility. It highlights advancements in donor‐acceptor COFs for targeted delivery and fluorescence‐aided cell uptake, while also considering the challenges in pore geometry customization.
Fariba Mehvari, Vahid Ramezanzade, Parvin Asadi, Nem Singh, Jaewon Kim, Mohammad Dinari, Jong Seung Kim   +6 more
wiley   +1 more source

How latanoprost changed glaucoma management

Acta Ophthalmologica, Volume 102, Issue 2, Page e140-e155, March 2024.
Abstract Glaucoma is currently considered one of the leading causes of severe visual impairment and blindness worldwide. Topical medical therapy represents the treatment of choice for many glaucoma patients. Introduction of latanoprost, 25 years ago, with an entirely new mechanism of action from that of the antiglaucoma drugs used up to that time was a
Maria Francesca Cordeiro, Stefano Gandolfi, Konstantin Gugleta, Eduardo M. Normando, Francesco Oddone   +4 more
wiley   +1 more source

Preliminary evaluation of the efficacy and safety of brimonidine for general anesthesia

BMC Anesthesiology, 2021
Background To determine the hypnotic and analgesic effects of brimonidine, and evaluate its efficacy and safety for general anesthesia. Potentiation of pentobarbital sleeping time following brimonidine administration was observed in mice, as was the ...
Chen Bin, Wang Xiaohui, Shi Mengrou, Li Xin, Zhang Ting, Gao Ping   +5 more
doaj   +1 more source

Low expression of TGF‐β2 and matrilin2 in human aqueous humour with acute primary angle closure

Journal of Cellular and Molecular Medicine, Volume 28, Issue 3, February 2024.
Abstract Primary angle‐closure glaucoma (PACG) is the leading cause of irreversible blindness in the world. Angle closure induced by pupil block and secondary iris synechia is the fundamental pathology of the PACG. The molecular mechanisms of angle closure have not yet been clearly illustrated.
Liming Wang, Zhao Xu, Yaru Hong, Yan Liu, Xiaomin Zhang, Qiang Feng, Dandan Zhang, Kexi Chen, Guli Humaer Yiming, Xiaorong Li, Aihua Liu, Lijie Dong   +11 more
wiley   +1 more source

Clinical efficacy of treatment for subclinical-stage axial diabetic optic neuropathy

Journal of Ophthalmology, 2018
Background: There is no standard of therapy for the treatment of diabetic optic neuropathy (DON). Purpose: To assess the clinical efficacy of thioctic acid, topical brimonidine tartrate and a combination of vitamins В1, В6, and В12 in the management ...
M.A. Karliychuk, P.A. Bezditko
doaj   +1 more source

Recent Advances in the Use of Cubosomes as Drug Carriers with Special Emphasis on Topical Applications

Journal of Lipids, Volume 2024, Issue 1, 2024.
Topical drug delivery employing drug nanocarriers has shown prominent results in treating topical ailments, especially those confined to the skin and eyes. Conventional topical formulations persist with drug and disease‐related challenges during treatment. Various nanotechnology‐driven approaches have been adopted to mitigate the issues associated with
A. Gowri Nath, Prashant Dubey, Ankaj Kumar, Klaudi K. Vaiphei, Jessica M. Rosenholm, Kuldeep K. Bansal, Arvind Gulbake, Alexis Stamatikos   +7 more
wiley   +1 more source