Results 51 to 60 of about 1,511 (168)

Effects of intracameral tissue plasminogen activator injection on posterior capsular opacification, fibrin formation, and intraocular pressure in dogs after phacoemulsification

Veterinary Ophthalmology, EarlyView.
Abstract Objective To evaluate whether intracameral tissue plasminogen activator (tPA) injection is effective in regulating posterior capsular opacification (PCO), fibrin formation and intraocular pressure (IOP) after cataract surgery. Animal Studied Prospective study involving 30 eyes of 21 dogs that underwent phacoemulsification.
Kyulee Kim, Young‐Sun Kang, Joon Young Kim   +2 more
wiley   +1 more source

Synthesis of Novel Isoindolinones: Carbonic Anhydrase Inhibition Profiles, Antioxidant Potential, Antimicrobial Effect, Cytotoxicity and Anticancer Activity

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 4, April 2025.
Highly effective one‐pot synthesis of novel isoindolinones Inhibitory, antioxidant, antimicrobial cytotoxicity, and anticancer potentials of synthesized novel isoindolinone derivatives were investigated. ABSTRACT An efficient one‐pot method has been developed for synthesizing novel isoindolinone derivatives from 2‐benzoylbenzoic acid using ...
Yusuf Serdar Yazıcıoğlu, Şeydanur Elmas, Zeynep Kılıç, Murat Çelik, Buket Bakan, Ufuk Atmaca, Songül Bayrak   +6 more
wiley   +1 more source

Anticholinesterase and carbonic anhydrase inhibitory activities of natural carnosic acid derivatives: A comprehensive in vitro and in silico study

Archiv der Pharmazie, Volume 358, Issue 3, March 2025.
Carnosic acid derivatives were evaluated for their inhibitory activities against acetyl‐ and butyrylcholinesterases (AChE, BChE) and carbonic anhydrases (CAs). Rosmanol exhibited exceptional potency, surpassing tacrine and acetazolamide. Molecular docking, MM‐GBSA, and MD simulations confirmed strong binding and stability.
Zeynep Köksal, Halil Şenol
wiley   +1 more source

Papillomacular retinoschisis associated with glaucoma: Response to topical carbonic anhydrase inhibitor

American Journal of Ophthalmology Case Reports, 2020
Purpose: We report the clinical courses of two patients with papillomacular retinoschisis in eyes with advanced glaucomatous optic neuropathy. Observations: In case 1, a 67-year-old woman was diagnosed with papillomacular retinoschisis and normal tension
Masatoshi Haruta, So Handa, Shigeo Yoshida   +2 more
doaj  

Бринзоламид-индуцированная ретинопатия у новорожденных крыс: альтернативная животная модель неоваскулярной патологии сетчатки [PDF]

, 2013
Проблема неоваскуляризації сітківки штовхає дослідників до пошуку нових підходів до моделювання,діагностики та лікування неоангіоґенезу. В роботі вівчався вплив бринзоламід-індукованого системного ацидозу на неоваскуляризацію сітківки новонароджених ...
Белецкая, П.В., Гапунин, И.Д., Дёмин, Ю.А.   +2 more
core  

A case report of pediatric systemic juvenile xanthogranuloma

Malignancy Spectrum, Volume 2, Issue 1, Page 53-58, March 2025.
Abstract Background Juvenile xanthogranuloma (JXG) is a rare disorder that belongs to the broad group of non‐Langerhans cell histiocytosis. It is characterized by one or more nodules with predilection sites on the head, neck, and trunk, and lesions that may be several millimeters in diameter.
Feifei Liu, Man Hu, Rui Zhang, Zhigang Li, Hongyun Lian   +4 more
wiley   +1 more source

Ocular Distribution of Brimonidine and Brinzolamide after Topical Instillation of a 0.1% Brimonidine Tartrate and 1% Brinzolamide Fixed-Combination Ophthalmic Suspension: An Interventional Study

Journal of Clinical Medicine, 2023
Purpose: To evaluate the concentrations of brimonidine and brinzolamide in the vitreous and aqueous humor after instillation of a 0.1% brimonidine tartrate and 1% brinzolamide fixed-combination ophthalmic suspension. Methods: The present investigation involved patients with macular holes or idiopathic epiretinal membranes who were planning to undergo ...
Yusuke Orii, Eriko Kunikane, Yutaka Yamada, Masakazu Morioka, Kentaro Iwasaki, Shogo Arimura, Akemi Mizuno, Masaru Inatani   +7 more
openaire   +2 more sources

A patient preference comparison of Azarga™ (brinzolamide/timolol fixed combination) vs Cosopt® (dorzolamide/timolol fixed combination) in patients with open-angle glaucoma or ocular hypertension

Clinical Ophthalmology, 2008
Thomas K Mundorf1, Steven H Rauchman2, Robert D Williams3, Ricardo Notivol4, Brinzolamide/Timolol Preference Study Group51Mundorf Eye Center, Charlotte, NC, USA; 2North Valley Eye Medical Group, Mission Hills, CA, USA; 3Taustine Eye Center, Louisville ...
Thomas K Mundorf, Steven H Rauchman, Robert D Williams, Ricardo Notivol, Brinzolamide/Timolol Preference Study Group   +4 more
doaj  

A personalized approach to preclinical diagnosis and initial therapy of primary glaucoma based on a comprehensive structural and functional examination. A clinical case

Российский офтальмологический журнал, 2022
The principles of personalized approach to early diagnosis and monitoring of primary glaucoma are shown by a clinical example. We analyzed the potentials of contemporary electrophysiological tests for preclinically diagnosing glaucoma optic neuropathy ...
A. N. Zhuravleva, M. V. Zueva, S. Y. Petrov, M. O. Kirillova, S. M. Kosakyan, I. V. Tsapenko   +5 more
doaj   +1 more source

Fish Fin‐Derived Non‐Invasive Flexible Bioinspired Contact Lens for Continuous Ophthalmic Drug Delivery

Advanced Science, Volume 12, Issue 6, February 10, 2025.
Inspired by the structure and reciprocating motion of fish dorsal fins, a drug‐eluting contact lens based on deformable microstructures for non‐invasive drug delivery is developed. The drug release rate can be adaptively adjusted to intraocular pressure changes and proactively regulated by cyclic ocular loads, enabling it to respond to elevated ...
Xu Li, Hui Li, Zihao Wang, Xianda Wang, Jinlong Zhang, Fengjiao Bin, Wei Chen, Hongyang Li, Dongmei Huo, Dengbao Xiao   +9 more
wiley   +1 more source