A combined analysis of five observational studies evaluating the efficacy and tolerability of bimatoprost/timolol fixed combination in patients with primary open-angle glaucoma or ocular hypertension [PDF]
OBJECTIVE: The aim of this study was to evaluate the safety and efficacy of a fixed combination of bimatoprost 0.03% and timolol (BTFC) in a clinical setting, in a large sample of patients with primary open-angle glaucoma or ocular hypertension and ...
Bron, Alain +6 more
core +3 more sources
Upper limits of intraocular pressure in glaucoma clinical trials [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110560/1/ceo12357 ...
DeMill, David L +3 more
core +1 more source
Calculating total health service utilisation and costs from routinely collected electronic health records using the example of patients with irritable bowel syndrome before and after their first gastroenterology appointment [PDF]
INTRODUCTION: Health economic models are increasingly important in funding decisions but most are based on data, which may therefore not represent the general population.
A Basu +49 more
core +2 more sources
Magnetic Resonance Imaging of Optic Nerve Traction During Adduction in Primary Open-Angle Glaucoma With Normal Intraocular Pressure. [PDF]
PurposeWe used magnetic resonance imaging (MRI) to ascertain effects of optic nerve (ON) traction in adduction, a phenomenon proposed as neuropathic in primary open-angle glaucoma (POAG).MethodsSeventeen patients with POAG and maximal IOP ≤ 20 mm Hg, and
Bonelli, Laura +8 more
core +1 more source
Two Cases of Hallermann-Streiff Syndrome with Retinal Abnormalities [PDF]
Hallermann-Streiff syndrome is a rare congenital disorder that is characterized by malformations of the craniofacial region with ocular abnormalities. Some ophthalmic signs can be observed in early age and some in adulthood.
Bausz Mária +4 more
core +1 more source
Expression profile of CREB knockdown in myeloid leukemia cells. [PDF]
BackgroundThe cAMP Response Element Binding Protein, CREB, is a transcription factor that regulates cell proliferation, differentiation, and survival in several model systems, including neuronal and hematopoietic cells.
Cheng, Jerry C +6 more
core +2 more sources
AIM: To evaluate the short-term effect of the fixed combination of brinzolamide-timolol on the ocular surface in glaucoma patients.METHODS: This is a prospective study of 23 eyes of 23 patients with newly diagnosed glaucoma.
Penpe Gul Firat +5 more
doaj +1 more source
The physiological role of carbonic anhydrases in pH and ion regulation is crucial to insect survival. We examined the toxic and neurophysiological effects of five carbonic anhydrase inhibitors (CAIs) against Aedes aegypti.
Sheena A. M. Francis +3 more
doaj +1 more source
The Major Role of Clinicians in the Discovery of Off-Label Drug Therapies [PDF]
Objective: To determine, through a review of the medical literature and author contact, the role of clinicians in the discovery of off label use of Food and Drug Administration approved prescription drugs.
Ali, Ayfer +2 more
core +2 more sources

