Results 1 to 10 of about 743 (109)

Brivaracetam substituting other antiepileptic treatments: Results of a retrospective study in German epilepsy centers

open access: yesEpilepsia Open, 2020
Objective To evaluate the success of initiation of adjunctive brivaracetam in patients who required a change in antiepileptic drug (AED) regimen and substituted at least one AED with brivaracetam.
Holger Lerche   +7 more
doaj   +2 more sources

Overnight switch from levetiracetam to brivaracetam. Safety and tolerability [PDF]

open access: yesEpilepsy & Behavior Reports, 2021
Brivaracetam is a newer antiseizure medication than levetiracetam. It has a more selective action on the synaptic vesicle glycoprotein 2A binding site, and it seems to provide a more favorable neuropsychiatric profile. The aim of this study was to assess
L. Abraira   +6 more
doaj   +2 more sources

Brivaracetam attenuates pain behaviors in a murine model of neuropathic pain

open access: yesMolecular Pain, 2019
Background The antiseizure racetams may provide novel molecular insights into neuropathic pain due to their unique mechanism involving synaptic vesicle glycoprotein 2A.
Solomiya Tsymbalyuk   +7 more
doaj   +3 more sources

Brivaracetam: A Novel Antiepileptic Drug for Focal-Onset Seizures

open access: yesTherapeutic Advances in Neurological Disorders, 2018
Brivaracetam (BRV), the n -propyl analogue of levetiracetam (LEV), is the latest antiepileptic drug (AED) to be licensed in Europe and the USA for the adjunctive treatment of focal-onset seizures with or without secondary generalization in patients aged ...
Linda J Stephen, Martin J Brodie
exaly   +2 more sources

Third generation antiepileptic drugs: mechanism of action, pharmacokinetics, interaction and use in childhood

open access: yesЭпилепсия и пароксизмальные состояния, 2023
The review considers pharmacological characteristics of new antiepileptic drugs (AEDs) of the third generation such as eslicarbazepine, lacosamide, retigabine, perampanel, everolimus, brivaracetam, zonisamide.
Z. G. Tadtaeva   +3 more
doaj   +1 more source

Α Multicenter Retrospective Study Evaluating Brivaracetam in the Treatment of Epilepsies in Clinical Practice

open access: yesPharmaceuticals, 2021
Brivaracetam (BRV) is the latest approved antiepileptic drug. The aim of the study was to evaluate the efficacy and tolerability of BRV in everyday clinical practice.
Maria Stefanatou   +11 more
doaj   +1 more source

EFFICACY OF BRIVARACETAM IN PEDIATRIC EPILEPSY: AN UP-TO-DATE [PDF]

open access: yesEuromediterranean Biomedical Journal, 2021
Among the newest antiepileptic drugs, brivaracetam (BRV), previously known as “ucb34714”, is one of the most interesting molecules available, increasingly getting the attention of researchers.
Antonio Nicotera
doaj   +1 more source

The Integrated Effects of Brivaracetam, a Selective Analog of Levetiracetam, on Ionic Currents and Neuronal Excitability

open access: yesBiomedicines, 2021
Brivaracetam (BRV) is recognized as a novel third-generation antiepileptic drug approved for the treatment of epilepsy. Emerging evidence has demonstrated that it has potentially better efficacy and tolerability than its analog, Levetiracetam (LEV). This,
Te-Yu Hung, Sheng-Nan Wu, Chin-Wei Huang
doaj   +1 more source

Brivaracetam exhibits mild pro-inflammatory features in an in vitro astrocyte-microglia co-culture model of inflammation

open access: yesFrontiers in Cellular Neuroscience, 2022
Implications of glia in the pathophysiology of epilepsy raise the question of how these cells besides neurons are responsive to antiseizure medications (ASMs).
Fatme Seval Ismail   +5 more
doaj   +1 more source

The Effect of Treatment for Epilepsy Associated with Malignant Neoplasms of the Brain: a Literature Review

open access: yesКреативная хирургия и онкология, 2023
Introduction. Epilepsy is a frequent complication in patients with malignant neoplasms of the brain. However, despite an extensive number of studies, anticonvulsants with antitumor activity have not been studied enough.
Y. Wang   +6 more
doaj   +1 more source

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