IL-13R alpha 2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca2+ signaling [PDF]
Background: The interleukins IL-4 and IL-13 play a key role in the pathophysiology of asthma. The interleukin receptor IL-13R alpha 2 is believed to act as a decoy receptor, but until now, the functional significance of IL-13R alpha 2 remains vague ...
Bergner, Albrecht+5 more
core +1 more source
Concentrations of Cysteinyl Leukotrienes in Various Biological Fluids of Children with Bronchial Asthma, Atopic Dermatitis and Food Protein Induced Enterocolitis [PDF]
Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma ...
Haiduchyk, H. (Halyna)+1 more
core +4 more sources
Background Bronchial asthma may mimic different diseases regarding their similar clinical presentations, so accurate assessment is required to exclude other possible diagnosis before confirming the diagnosis of bronchial asthma.
Samah M. Shehata+2 more
doaj +1 more source
Safety, tolerability, and impact on allergic inflammation of autologous E.coli autovaccine in the treatment of house dust mite asthma - a prospective open clinical trial [PDF]
Background: Asthma is increasing worldwide and results from a complex immunological interaction between genetic susceptibility and environmental factors. Autovaccination with E.
AE Wright+25 more
core +3 more sources
Bronchial artery aneurysm presenting with epigastric pain that improves with vomiting
A 64‐year‐old man presented to the emergency department with a chief complaint of epigastric pain that improved with vomiting. He was initially treated for gastrointestinal disease, but computed tomography (CT) showed a mediastinal haematoma and contrast‐
Kazuki Hayashi, Jun Hanaoka, Yusuke Kita
doaj +1 more source
Middle Lobe Syndrome Associated with Bronchial Anthracofibrosis
Bronchial anthracofibrosis has been defined as airway narrowing associated with dark pigmentation on bronchoscopy without an appropriate history of pneumoconiosis or smoking. We present a case of a 67-year-old, non-smoking female patient who was referred
Ugur Gonlugur+2 more
doaj +1 more source
Transcriptional down-regulation of suppressor of cytokine signaling (SOCS)-3 in chronic obstructive pulmonary disease [PDF]
Background: Tobacco is a leading environmental factor in the initiation of respiratory diseases and causes chronic obstructive pulmonary disease (COPD).
Dinh, Q. Thai+6 more
core +1 more source
New targets for resolution of airway remodeling in obstructive lung diseases. [PDF]
Airway remodeling (AR) is a progressive pathological feature of the obstructive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).
Deshpande, Deepak A.+2 more
core +2 more sources
Weakly Supervised Airway Orifice Segmentation in Video Bronchoscopy [PDF]
Video bronchoscopy is routinely conducted for biopsies of lung tissue suspected for cancer, monitoring of COPD patients and clarification of acute respiratory problems at intensive care units. The navigation within complex bronchial trees is particularly challenging and physically demanding, requiring long-term experiences of physicians.
arxiv +1 more source
Detection of Rs9939609 Polymorphism of Fto Gene and Rs324011 Polymorphism of Stat6 Gene and Severity Degree of Bronchial Asthma Associated with Obesity [PDF]
The aim of this research was to analyze the distribution of FTO and STAT6 genes polymorphism in patients with bronchial asthma (BA), associated with obesity (Ob) depending on the main disease severity degree.Materials and methods.
Fediv, A. (Alexander)+1 more
core +2 more sources