Results 11 to 20 of about 16,360 (203)

Protective effects of different doses of inhaled fenoterol on methacholine-induced bronchoconstriction in asthmatic children [PDF]

São Paulo Medical Journal, 1998
OBJECTIVE: To evaluate the protective effect of different doses of inhaled fenoterol (F) on bronchoconstriction induced by methacholine (M). DESIGN: randomized double-blind study. SETTING: Referrence center. PARTICIPANTS: 9 children (aged from 7 to 15
Irma Douglas Gomez, Marilia de Dirceu Silva, Maria Poliana Bueno, Dirceu Solé, Charles Kirov Naspitz   +4 more
doaj   +2 more sources

Exacerbations and Management of Asthma in Viral Lower Respiratory Tract Infections: The Significance of Immunoglobulin E. [PDF]

Immun Inflamm Dis
ABSTRACT Background Viral‐respiratory infections are the most prevalent illness among humans. A viral infection affecting lower respiratory tract infections (LRTI) is a critical health concern worldwide. The COVID‐19 pandemic has significantly impacted respiratory health, particularly in individuals with asthma.
Akhavan M, Yousefi P, Tabibzadeh A.
europepmc   +2 more sources

Asthma in Patients With Confirmed Pulmonary Sarcoidosis. [PDF]

Can Respir J
Pulmonary sarcoidosis and asthma can present identical symptoms, making clinical evaluation difficult if the two diseases overlap. Diagnostic challenges often lead to either overdiagnosis of asthma in patients with confirmed sarcoidosis or withholding appropriate asthma treatment.
Lewandowska AA, Waśniowska D, Kołodziej M, Mirus-Arabik H, Gaczkowska A, Duszyńska O, Bułat K, Graczyk M, Rybacki C.   +8 more
europepmc   +2 more sources

Prevalence and triggers of self-reported nasal hyperreactivity in adults with asthma

World Allergy Organization Journal, 2020
Background: Nasal hyperreactivity (NHR) is a common feature of various rhinitis subtypes and represents a novel phenotype of rhinitis. It is being reported in two-thirds of adult rhinitis patients irrespective of the atopic status. Data on the prevalence
Jef Feijen, Sven F. Seys, Brecht Steelant, Dominique M.A. Bullens, Lieven J. Dupont, Maria García-Cruz, Alejandro Jimenez-Chobillón, Désirée Larenas-Linnemann, Laura Van Gerven, Wytske J. Fokkens, Ioana Agache, Peter W. Hellings   +11 more
doaj   +1 more source

The relation between nonspecific hyperreactivity of the airways and atopic constitution in asthmatics [PDF]

Vojnosanitetski Pregled, 2016
Background/Aim. Hyperreactivity of the airways caused by inflammation in asthmatics is the most important pathophysiological change. It represents a suitable ground that in the presence of risk factors and the drivers of asthma, asthmatic attack occurs ...
Novković Dobrivoje, Petrović Marina, Živković Vladan, Baletić Nenad   +3 more
doaj   +1 more source

The Lung Function Impairment in Non-Atopic Patients With Chronic Rhinosinusitis and Its Correlation Analysis [PDF]

Clinical and Experimental Otorhinolaryngology, 2016
Objectives Chronic rhinosinusitis (CRS) is common disease in otorhinolaryngology and will lead to lower airway abnormality. However, the only lung function in CRS patients and associated factors have not been much studied.
Linghao Zhang, Lu Zhang, Chun-Hong Zhang, Xiao-Bi Fang, Zhen-Xiao Huang, Qing-Yuan Shi, Li-Ping Wu, Peng Wu, Zhen-Zhen Wang, Zhi-Su Liao   +9 more
doaj   +1 more source

IL-13R alpha 2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca2+ signaling [PDF]

, 2007
Background: The interleukins IL-4 and IL-13 play a key role in the pathophysiology of asthma. The interleukin receptor IL-13R alpha 2 is believed to act as a decoy receptor, but until now, the functional significance of IL-13R alpha 2 remains vague ...
Bergner, Albrecht, Gamarra, Fernando, Huber, Rudolf M., Joerres, Rudolf A., Kellner, Julia, Welsch, Ulrich   +5 more
core   +1 more source

Epithelial barrier dysfunction in bronchial asthma

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2022
The pathogenesis of bronchial asthma is based on chronic inflammation as a response to etiological factors. It causes bron-chial hyperreactivity, remodeling of the respiratory tract and hypersecretion of mucus.
R. N. Khramova, T. I. Eliseeva, T. E. Potemina   +2 more
doaj   +1 more source

Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]

, 2013
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer, Becky J. Proskocil, Borish L, Crain EF, Crinnion WJ, David B. Jacoby, Donald A. Bruun, Gallo MA, Grodzki AC, Lu C, Nico van Rooijen, Pamela J. Lein, Rozyk KJ   +12 more
core   +1 more source

A Guinea Pig Model of Airway Smooth Muscle Hyperreactivity Induced by Chronic Allergic Lung Inflammation: Contribution of Epithelium and Oxidative Stress

Frontiers in Pharmacology, 2019
Asthma is a heterogeneous disease of the airways characterized by chronic inflammation associated with bronchial and smooth muscle hyperresponsiveness. Currently, different murine models for the study of asthma show poor bronchial hyperresponsiveness due
Luiz Henrique César Vasconcelos, Maria da Conceição Correia Silva, Alana Cristina Costa, Giuliana Amanda de Oliveira, Iara Leão Luna de Souza, Fernando Ramos Queiroga, Layanne Cabral da Cunha Araujo, Glêbia Alexa Cardoso, Renato Fraga Righetti, Renato Fraga Righetti, Alexandre Sérgio Silva, Alexandre Sérgio Silva, Patrícia Mirella da Silva, Patrícia Mirella da Silva, Carla Roberta de Oliveira Carvalho, Carla Roberta de Oliveira Carvalho, Giciane Carvalho Vieira, Iolanda de Fátima Lopes Calvo Tibério, Fabiana de Andrade Cavalcante, Fabiana de Andrade Cavalcante, Bagnólia Araújo da Silva, Bagnólia Araújo da Silva   +21 more
doaj   +1 more source