Results 21 to 30 of about 58,742 (212)

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, EarlyView.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources

Bronchiectasis and increased mortality in patients with corticosteroid-dependent severe asthma: a nationwide population study

Therapeutic Advances in Respiratory Disease, 2020
Background: Long-term corticosteroid (CS) use is associated with increased mortality in patients with asthma, and comorbid bronchiectasis is also associated with frequent asthma exacerbation and increased healthcare use.
Hayoung Choi, Hyun Lee, Jiin Ryu, Sung Jun Chung, Dong Won Park, Jang Won Sohn, Ho Joo Yoon, Sang-Heon Kim   +7 more
doaj   +1 more source

Bronchiectasis-associated hospitalizations in Germany, 2005-2011: a population-based study of disease burden and trends. [PDF]

PLoS ONE, 2013
BACKGROUND: Representative population-based data on the epidemiology of bronchiectasis in Europe are limited. The aim of the present study was to investigate the current burden and the trends of bronchiectasis-associated hospitalizations and associated ...
Felix C Ringshausen, Andrés de Roux, Mathias W Pletz, Nina Hämäläinen, Tobias Welte, Jessica Rademacher   +5 more
doaj   +1 more source

Common variable immunodeficiency disorder - An uncommon cause for bronchiectasis

Lung India, 2014
Bronchiectasis continues to be a common respiratory problem of varied etiology. Common variable immunodeficiency disorder (CVID) is an uncommon cause for bronchiectasis.
Manoj Kumar Panigrahi
doaj   +1 more source

The clinical impact of self‐reported symptoms of chronic rhinosinusitis in people with bronchiectasis

Immunity, Inflammation and Disease, 2022
Background Chronic rhinosinusitis affects 62% of adults with bronchiectasis and is linked to greater bronchiectasis severity. However, the impact of symptoms of chronic rhinosinusitis on disease‐specific and cough‐related quality of life is unknown ...
Annemarie L. Lee, Caroline H. H. Nicolson, Janet Bondarenko, Brenda M. Button, Samantha Ellis, Robert G. Stirling, Mark Hew   +6 more
doaj   +1 more source

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis‐Associated Interstitial Lung Disease Risk

Arthritis Care &Research, Accepted Article.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase (MMP)‐7, and serum anti‐malondialdehyde‐acetaldehyde (anti‐MAA) antibody for RA‐associated interstitial lung disease risk stratification. Methods Using a multicenter cohort of US veterans with RA, we performed a cross‐
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

Evaluation of symptoms and risks in stable chronic obstructive pulmonary disease patients with radiographic bronchiectasis

Chronic Diseases and Translational Medicine, 2017
Objective: To investigate the presence of previously undiagnosed radiographic bronchiectasis in stable chronic obstructive pulmonary disease (COPD) patients using high resolution computed tomography (HRCT) and to evaluate the effect of radiographic ...
Rong-Bao Zhang, Fei Yuan, Xing-Yu Tan, Quan-Ying He   +3 more
doaj   +1 more source

Marked Long‐term Improvement in Lung Function in Melanoma Differentiation‐associated Protein 5 (MDA5) Antibody Positive Dermatomyositis Patients: Experience of a Single Center Longitudinal Cohort in North America

Arthritis Care &Research, Accepted Article.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah, Sangmee S Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Multivariate Contrastive Predictive Coding with Sliding Windows for Disease Prediction from Electronic Health Records

Advanced Intelligent Systems, EarlyView.
Adaptive multi‐indicator contrastive predictive coding is introduced as a self‐supervised pretraining framework for multivariate EHR time series. An adaptive sliding‐window algorithm and 2D convolutional neural network encoder capture localized temporal patterns and global indicator dependencies, enabling label‐efficient disease prediction that ...
Hongxu Yuan, Xiaozhu Jing, Yuzheng Yan, Wuman Luo   +3 more
wiley   +1 more source

Soft Artificial Ciliary Brush with Integrated Haptic Feedback for Efficient Airway Mucus Cleaning

Advanced Intelligent Systems, EarlyView.
A fundamental mucus cleaning mechanism is reported, which utilizes both artificial cilia mechanical sweeping and suction‐based mucus cleaning. A novel haptic feedback interface for the artificial cilia provides touch feedback on tissue contact, enhancing operator control and safety.
Zhongming Lyu, Yusheng Wang, Ruijian Ge, Darren Wang, Matthew Bacchetta, Caitlin T. Demarest, Fabien Maldonado, Xiaoguang Dong   +7 more
wiley   +1 more source