Results 141 to 150 of about 227,715 (371)

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Bacterial Outer Membrane Vesicles Induce Vitronectin Release Into the Bronchoalveolar Space Conferring Protection From Complement-Mediated Killing

Frontiers in Microbiology, 2018
Pathogens causing pneumonia utilize the complement regulator vitronectin to evade complement-mediated killing. Although vitronectin is associated with several chronic lung diseases, the role of bronchoalveolar vitronectin in pneumonia has not been ...
Magnus Paulsson, Karlhans F. Che, Jonas Ahl, Johan Tham, Linda Sandblad, Margaretha E. Smith, Ingemar Qvarfordt, Yu-Ching Su, Anders Lindén, Anders Lindén, Kristian Riesbeck   +10 more
doaj   +1 more source

Metastability and nucleation in the dilute fluid phase of a simple model of globular proteins [PDF]

arXiv, 1999
The dilute fluid phase of model globular proteins is studied. The model possesses a fluid-fluid transition buried within the fluid-crystal coexistence region, as do some globular proteins. If this fluid-fluid transition is not buried deep inside the fluid-crystal coexistence region the crystalline phase does not nucleate within the dilute fluid.
arxiv  

Heterologous matrix metalloproteinase gene promoter activity allows In Vivo real-time imaging of Bleomycin-induced Lung fibrosis in transiently transgenized mice [PDF]

, 2017
Idiopathic pulmonary fibrosis is a very common interstitial lung disease derived from chronic inflammatory insults, characterized by massive scar tissue deposition that causes the progressive loss of lung function and subsequent death for respiratory ...
Donofrio, Gaetano, Macchi, Francesca, Pompilio, Daniela, Ravanetti, Francesca, Ruscitti, Francesca, Stellari, Fabio Franco, Tebaldi, Giulia, Verna, Andrea Elizabeth, Villetti, Gino   +8 more
core   +1 more source

Cell Recovery in Bronchoalveolar Lavage Fluid in Smokers Is Dependent on Cumulative Smoking History

PLoS ONE, 2012
Background Smoking is a risk factor for various lung diseases in which BAL may be used as a part of a clinical investigation. Interpretation of BAL fluid cellularity is however difficult due to high variability, in particular among smokers. In this study
R. Karimi, G. Tornling, J. Grunewald, A. Eklund, C. Sköld   +4 more
semanticscholar   +1 more source

CXCL14 increase dendritic cell antigen presentation and promote asthma immune response

Pediatric Discovery, EarlyView.
RNA‐seq showed that C‐X‐C motif chemokine ligand 14 (CXCL14) was upregulated in bone marrow dendritic cells after house dust mites (HDM) stimulation, and its function was related to signal molecule interaction and the immune system. The expression of CXCL14 was increased in the HDM‐induced allergic asthma model.
Wenjie Wu, Fengxia Ding, Yan Li, Zhou Fu
wiley   +1 more source

Supercooled fluid-fluid phase transition in three dimensions from a soft-core potential [PDF]

arXiv, 2000
To study the possibility of a fluid-fluid phase transition, we analyze a three-dimensional soft-core isotropic potential for a one-component system. We utilize two independent numerical approaches, (i) integral equation in the hypernetted-chain approximation and (ii) molecular dynamics simulations, and find for both approaches a fluid-fluid phase ...
arxiv  

Microbiota diversity and differences in the respiratory tract of children with pneumonia

Pediatric Investigation, EarlyView.
Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge, Lingyun Hou, Jintao Guo, Xuejing Lv, Yungang Yang   +4 more
wiley   +1 more source

Effects of fluticasone propionate inhalation on levels of arachidonic acid metabolites in patients with chronic obstructive pulmonary disease

Mediators of Inflammation, 2001
Background: In smoking COPD patients the bronchoalveolar lavage (BAL) fluid contains high numbers of inflammatory cells. These cells might produce arachidonic acid (AA) metabolites, which contribute to inflammation and an increased bronchomotor tone.
Gert T. Verhoeven, Ingrid M. Garrelds, Henk C. Hoogsteden, Freek J. Zijlstra   +3 more
doaj   +1 more source

Characterization of the innate immune response to chronic aspiration in a novel rodent model

Respiratory Research, 2007
Background Although chronic aspiration has been associated with several pulmonary diseases, the inflammatory response has not been characterized. A novel rodent model of chronic aspiration was therefore developed in order to investigate the resulting ...
Lin Shu S, Yoon Yonghan, Cantu Edward, Hsieh Chong-Chao, Li Bin, Hartwig Matthew G, Lee Sean M, Appel James Z, Parker William, Davis R Duane   +9 more
doaj   +1 more source