Deep inspiration and the emergence of ventilation defects during bronchoconstriction: a computational study. [PDF]
Deep inspirations (DIs) have a dilatory effect on airway smooth muscle (ASM) that helps to prevent or reduce more severe bronchoconstriction in healthy individuals. However, this bronchodilation appears to fail in some asthmatic patients or under certain
Amir H Golnabi+3 more
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Background: Cough variant asthma (CVA) is recognized as a precursor of bronchial asthma (BA). However, the cough response to bronchoconstriction differs between these similar diseases.
Kenta Yamamura+11 more
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Vagus nerve stimulation as a potential treatment for acute asthmatic bronchoconstriction: a systematic review [PDF]
ObjectiveVagus nerve stimulation (VNS) is a therapeutic option for diseases such as epilepsy and depression. Given that the smooth muscle of the bronchi is innervated by the vagus nerve, VNS could aid in treating pathologies of the respiratory system ...
Elizabeth Di Flumeri+8 more
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Circulating Antimicrobial Peptides as Biomarkers of Inflammation and Airway Dysfunction After Marathon Running [PDF]
Marathon running exerts physical stress and may lead to transient immune dysregulation, increasing susceptibility to airway inflammation and exercise-induced bronchoconstriction (EIB).
Marie-Therese Lingitz+8 more
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Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse [PDF]
Background It has been proposed that serotonin (5-HT)-mediated constriction of the murine trachea is largely dependent on acetylcholine (ACh) released from the epithelium.
Koepsell Hermann+8 more
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Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices. [PDF]
Airway remodelling, including smooth muscle remodelling, is a primary cause of airflow limitation in asthma. Recent evidence links bronchoconstriction to airway remodelling in asthma. The mechanisms involved are poorly understood.
Tjitske A Oenema+5 more
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Bronchoconstriction: a potential missing link in airway remodelling [PDF]
In asthma, progressive structural changes of the airway wall are collectively termed airway remodelling. Despite its deleterious effect on lung function, airway remodelling is incompletely understood.
Michael J. O'Sullivan+2 more
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Excipients of inhaled medications with potential to cause adverse reactions [PDF]
Introduction: In addition to the active pharmaceutical ingredient (API), the composition of the medicines also includes excipients which are only ideally completely pharmacologically inactive. It has been shown that excipients in inhaled preparations can
Kusonić Dejan Ž.+7 more
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Cinnamon is one of the most commonly used spices worldwide. In some Arab countries, cinnamon is used with other ingredients to relieve bronchospasm and treatment of airways-related disorders.
Najeeb Ur Rehman+7 more
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Bronchoconstriction following instillation of phenylephrine eye drops in premature infants with bronchopulmonary dysplasia: two cases report [PDF]
Premature infants requiring an ophthalmic examination or even surgery for retinopathy of prematurity (ROP) have a high prevalence of co-existing bronchopulmonary dysplasia (BPD). Reactive airway is one of the clinical presentations of BPD.
Hyun Jee Kim+2 more
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