Results 1 to 10 of about 31,442 (240)
Deep inspiration and the emergence of ventilation defects during bronchoconstriction: a computational study. [PDF]
PLoS ONE, 2014 Deep inspirations (DIs) have a dilatory effect on airway smooth muscle (ASM) that helps to prevent or reduce more severe bronchoconstriction in healthy individuals. However, this bronchodilation appears to fail in some asthmatic patients or under certain
Amir H Golnabi +3 more
doaj +5 more sources
Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyperresponsiveness
Nature Neuroscience, 2017 Asthma, accompanied by lung inflammation, bronchoconstriction and airway hyper-responsiveness, is a significant public health burden. Here we report that Mas-related G protein-coupled receptors (Mrgprs) are expressed in a subset of vagal sensory neurons ...
Liang Han +12 more
semanticscholar +3 more sources
Management of Exercise-Induced Bronchoconstriction [PDF]
Canadian Respiratory Journal, 1999 Exercise-induced bronchoconstriction (EIB) is a common clinical manifestation of asthma, occurring in 70% to 80% of asthmatics. Evidence suggests that exercise and the ensuing bronchoconstriction do not contribute to a worsening of asthmatic inflammation.
Mark D Inman
doaj +3 more sources
Acetylcholine beyond bronchoconstriction
Trends in Pharmacological Sciences, 2015 Acetylcholine is the primary parasympathetic neurotrans. mitter in the airways, where it not only induces bronchoconstriction and mucus secretion, but also regulates airway inflammation and remodeling. In this review, we propose that these effects are all primarily mediated via the muscarinic M-3 receptor.
Kistemaker, Loes E M, Gosens, Reinoud
openaire +2 more sources
Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse [PDF]
Respiratory Research, 2006 Background It has been proposed that serotonin (5-HT)-mediated constriction of the murine trachea is largely dependent on acetylcholine (ACh) released from the epithelium.
Koepsell Hermann +8 more
doaj +3 more sources
Frontiers in Physiology, 2022 Mechanosensitive vagal afferents in the lung, rapidly and slowly adapting receptors (RARs and SARs, respectively), play an important role in eliciting the reflexes that regulate the normal airway function.
You Shuei Lin +5 more
doaj +1 more source
Bronchoconstriction following instillation of phenylephrine eye drops in premature infants with bronchopulmonary dysplasia: two cases report [PDF]
Korean Journal of Anesthesiology, 2015 Premature infants requiring an ophthalmic examination or even surgery for retinopathy of prematurity (ROP) have a high prevalence of co-existing bronchopulmonary dysplasia (BPD). Reactive airway is one of the clinical presentations of BPD.
Hyun Jee Kim +2 more
doaj +1 more source
Bronchoconstriction: a potential missing link in airway remodelling [PDF]
Open Biology, 2020 In asthma, progressive structural changes of the airway wall are collectively termed airway remodelling. Despite its deleterious effect on lung function, airway remodelling is incompletely understood.
Michael J. O'Sullivan +2 more
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Excipients of inhaled medications with potential to cause adverse reactions [PDF]
Hospital Pharmacology, 2021 Introduction: In addition to the active pharmaceutical ingredient (API), the composition of the medicines also includes excipients which are only ideally completely pharmacologically inactive. It has been shown that excipients in inhaled preparations can
Kusonić Dejan Ž. +7 more
doaj +1 more source
Allergology International, 2020 Background: Cough variant asthma (CVA) is recognized as a precursor of bronchial asthma (BA). However, the cough response to bronchoconstriction differs between these similar diseases.
Kenta Yamamura +11 more
doaj +1 more source