Results 91 to 100 of about 42,854 (297)

Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events (Review) [PDF]

open access: yes, 2009
Background Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are ...
Cates, CJ, Jaeschke, R, Lasserson, TJ
core   +1 more source

Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The carotid body develops aberrant high activity in chronic heart failure, resistant hypertension, obstructive sleep apnoea (OSA) and diabetes. Hyperactivity of the carotid body leads to both high tonicity and increased sensitivity of the arterial chemoreflex with resultant sympathoexcitation.
Tymoteusz Żera   +7 more
wiley   +1 more source

Gas exchange during exercise in habitually active asthmatic subjects [PDF]

open access: yes, 2005
We determined the relations among gas exchange, breathing mechanics, and airway inflammation during moderate- to maximum-intensity exercise in asthmatic subjects.
Dempsey, JA   +6 more
core   +1 more source

Steamed hay and alfalfa pellets for the management of severe equine asthma

open access: yesEquine Veterinary Journal, Volume 57, Issue 3, Page 756-765, May 2025.
Abstract Background Steaming hay significantly reduces respirable particles and provides a palatable alternative to dry hay for horses with asthma, but there are few prospective studies demonstrating the clinical efficacy of steamed hay. Objectives To compare the efficacy of alfalfa pellets and steamed hay in improving lung function and inflammation of
Antoine Symoens   +9 more
wiley   +1 more source

Preventing acute asthmatic symptoms by targeting a neuronal mechanism involving carotid body lysophosphatidic acid receptors

open access: yesNature Communications, 2018
Acute bronchoconstriction is the leading cause of asthmatic sudden death following allergen exposure. The authors show that the systemic increase of LPA following inhaled allergen or bradykinin challenge activates the carotid bodies through TRPV1 and LPA-
Nicholas G. Jendzjowsky   +8 more
doaj   +1 more source

Benralizumab and the integrated management of co‐morbid severe eosinophilic asthma with chronic rhinosinusitis with nasal polyps

open access: yesClinical and Translational Allergy, Volume 15, Issue 4, April 2025.
Abstract Background Type 2 (T2) inflammation, characterized by blood and airway eosinophilia, underlies severe eosinophilic asthma (SEA) and chronic rhinosinusitis with nasal polyps (CRSwNP). In line with the Global Airways theory, SEA and CRSwNP frequently co‐occur, creating a multimorbid phenotype.
Joaquim Mullol   +4 more
wiley   +1 more source

Mechanical correlates of dyspnea in bronchial asthma. [PDF]

open access: yes, 2013
We hypothesized that dyspnea and its descriptors, that is, chest tightness, inspiratory effort, unrewarded inspiration, and expiratory difficulty in asthma reflect different mechanisms of airflow obstruction and their perception varies with the severity ...
A., Antonelli   +8 more
core   +1 more source

Prevalence of exercise-induced bronchoconstriction and exercise-induced laryngeal obstruction in a general adolescent population

open access: yesThorax, 2014
Background Exercise-induced respiratory symptoms are common among adolescents. Exercise is a known stimulus for transient narrowing of the airways, such as exercise-induced bronchoconstriction (EIB) and exercise-induced laryngeal obstruction (EILO).
Henrik Johansson   +7 more
semanticscholar   +1 more source

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