Results 91 to 100 of about 35,906 (244)

Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Anaphylaxis is a life‐threatening immunoglobulin E (IgE)‐mediated type I hypersensitivity reaction with rising prevalence and burden. It involves mast cell degranulation upon cross‐linking of antigen on mast cell‐bound IgE. Mechanisms of IgE‐mediated anaphylaxis remain incompletely understood, particularly the induction of systemic symptoms ...
Ruchi Biswas, Jamie Moore Fried, Maria A. Curotto de Lafaille   +2 more
wiley   +1 more source

Preventing acute asthmatic symptoms by targeting a neuronal mechanism involving carotid body lysophosphatidic acid receptors

Nature Communications, 2018
Acute bronchoconstriction is the leading cause of asthmatic sudden death following allergen exposure. The authors show that the systemic increase of LPA following inhaled allergen or bradykinin challenge activates the carotid bodies through TRPV1 and LPA-
Nicholas G. Jendzjowsky, Arijit Roy, Nicole O. Barioni, Margaret M. Kelly, Francis H. Y. Green, Christopher N. Wyatt, Richard L. Pye, Luana Tenorio-Lopes, Richard J. A. Wilson   +8 more
doaj   +1 more source

Advances in the Gut‐Lung Axis and Bronchial Asthma: From Mechanisms to Therapeutic Potential

Clinical and Translational Allergy, Volume 15, Issue 12, December 2025.
ABSTRACT Background Bronchial asthma (hereafter referred to as asthma) is a heterogeneous disease characterized by chronic airway inflammation, airway hyperresponsiveness (AHR), and reversible airflow limitation. Recent advancements in the “gut‐lung” axis concept have elucidated the intricate immunometabolic crosstalk between the gastrointestinal tract
Ting Zheng, Yi Huang, Hongmei Yao
wiley   +1 more source

The inhibitory effect of anti-allergic agent suplatast tosilate (IPD–1151T) on methacholine- and allergen-induced bronchoconstriction in sensitized mice

Mediators of Inflammation, 2000
The influence of an anti-allergic agent, suplatast tosilate (IPD-1151T; (±)-[2-[4-(3-ethoxy–2-hydroxypropoxy)phenyl-carbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate) on allergic bronchoconstriction induced by allergen and methacholine (MCh) were ...
Kazuhito Asano, Tetsuya Mizutani, Toshikazu Shimane, Masataka Hisano, Tadashi Hisamitsu, Harumi Suzaki   +5 more
doaj   +1 more source

Verapamil Induces Calcium Influx in the Trachea

Journal of Pharmacological Sciences, 2008
Verapamil, a Ca2+entry blocker, can induce bronchorelaxation and bronchoconstriction. The mechanism of verapamil-induced bronchoconstriction is poorly understood.
Seham Mustafa, Abdulkareem Abdulraheem, Abdulhakeem Alsughayer   +2 more
doaj   +1 more source

Comparable reductions in hyperpnoea-induced bronchoconstriction and markers of airway inflammation after supplementation with 6·2 and 3·1 g/d of long-chain n-3 PUFA in adults with asthma [PDF]

, 2017
Although high dose n-3 PUFA supplementation reduces exercise- and hyperpnoea-induced bronchoconstriction (EIB/HIB), there are concurrent issues with cost, compliance and gastrointestinal discomfort. It is thus pertinent to establish the efficacy of lower
Alving, Daviskas, Dominick E. Shaw, Graham R. Sharpe, Kim G. Jackson, Kirsty A. Hunter, Michael A. Johnson, Nauseef, Neil C. Williams, Shapiro   +9 more
core   +3 more sources

bronchoconstriction

Citation: 'bronchoconstriction' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15525 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

A standard, single dose of inhaled terbutaline attenuates hyperpnoea-induced bronchoconstriction and mast cell activation in athletes [PDF]

, 2016
Release of broncho-active mediators from mast cells during exercise hyperpnoea is a key factor in the pathophysiology of exercise-induced bronchoconstriction (EIB).
A. J. Simpson, Anderson SD, B. Dahlén, Bierman EW, Bonini M, Bye PT, Carlsen KH, Haby MM, Howarth PH, J. R. Bood, L. M. Romer, Newman SP, O'Sullivan S, P. Kippelen, Peachell PT, S. D. Anderson, S.-E. Dahlén   +16 more
core   +2 more sources

Evaluation of Inhaled Colistin/Fosfomycin as an Adjunctive Treatment for Ventilator‐Associated Pneumonia: A Preliminary Study

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Ventilator‐associated pneumonia (VAP) caused by gram‐negative bacteria is associated with significant complications, mortality, and resource utilization. Over the past decade, there has been growing interest in using fosfomycin to treat multidrug‐resistant gram‐negative infections, particularly when limited viable options ...
Atousa Hakamifard, Mohammad Reza Mohammadi, Alireza Homayouni, Farzin Khorvash, Saeed Abbasi, Behrooz Ataei, Mahnaz Momenzadeh   +6 more
wiley   +1 more source

Exercise-Induced Changes in Exhaled NO Differentiates Asthma With or Without Fixed Airway Obstruction From COPD With Dynamic Hyperinflation. [PDF]

, 2016
Asthmatic patients with fixed airway obstruction (FAO) and patients with chronic obstructive pulmonary disease (COPD) share similarities in terms of irreversible pulmonary function impairment. Exhaled nitric oxide (eNO) has been documented as a marker of
Chen, LF, Chou, PC, Chung, KF, Huang, SY, Joa, WC, Kuo, HP, Lo, YL, Sheng, TF, Wang, CH, Wang, TY   +9 more
core   +1 more source