Results 101 to 110 of about 32,014 (200)

Mechanical correlates of dyspnea in bronchial asthma. [PDF]

open access: yes, 2013
We hypothesized that dyspnea and its descriptors, that is, chest tightness, inspiratory effort, unrewarded inspiration, and expiratory difficulty in asthma reflect different mechanisms of airflow obstruction and their perception varies with the severity ...
A., Antonelli   +8 more
core   +1 more source

Inhaled 5‐HT1B/1D Receptor Antagonist Attenuates Sumatriptan‐Induced Sensitization of Capsaicin‐Sensitive Lung Vagal Afferents: Implications for Preventing Sumatriptan‐Associated Adverse Chest Symptoms

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Our previous study suggests that sumatriptan‐induced chest discomfort is associated with hypersensitivity of CSLV afferents via 5‐HT1B/1D receptors on nerve endings. The present study demonstrates that inhaled 5‐HT1B/1D receptor antagonism suppresses this hypersensitivity without compromising antimigraine efficacy, supporting local pulmonary antagonism
Nai‐Ju Chan   +3 more
wiley   +1 more source

Insulin increases sensory nerve density and reflex bronchoconstriction in obese mice

open access: yesJCI Insight, 2022
Obesity-induced asthma responds poorly to all current pharmacological interventions, including steroids, suggesting that classic, eosinophilic inflammation is not a mechanism.
Gina N. Calco   +4 more
doaj   +1 more source

A prebiotic galactooligosaccharide mixture reduces severity of hyperpnoea-induced bronchoconstriction and markers of airway inflammation [PDF]

open access: yes, 2016
Gut microbes have a substantial influence on systemic immune function and allergic sensitisation. Manipulation of the gut microbiome through prebiotics may provide a potential strategy to influence the immunopathology of asthma.
Alving   +10 more
core   +2 more sources

Completion of the Icatibant Outcome Survey and What We Learned

open access: yes
Clinical &Experimental Allergy, EarlyView.
Laurence Bouillet   +8 more
wiley   +1 more source

Ginkgolide B Alleviates Airway Inflammation in Hyperoxia Lung Injury

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Background Bronchopulmonary dysplasia (BPD) is a chronic lung disease characterized by inflammation, often caused by prolonged hyperoxia exposure in preterm infants. Platelet‐activating factor (PAF) is a potent inflammatory mediator, but its role in BPD is unclear.
Xuesong Wang   +5 more
wiley   +1 more source

Concentration of C-reactive protein, magnesium and calcium in children with acute bronchoconstriction before and after therapy with salbutamol [PDF]

open access: yes, 2010
Introduction: In childhood, bronchoobstruction is mostly caused by respiratory viral infections. The aim of this study was to find out possible changes in serum concentration of magnesium and calcium (participants in bronchoconstriction), and ...
Ivan Pavic   +5 more
core   +2 more sources

A standard, single dose of inhaled terbutaline attenuates hyperpnoea-induced bronchoconstriction and mast cell activation in athletes [PDF]

open access: yes, 2016
Release of broncho-active mediators from mast cells during exercise hyperpnoea is a key factor in the pathophysiology of exercise-induced bronchoconstriction (EIB).
A. J. Simpson   +16 more
core   +2 more sources

Are Phenotypic Baseline Characteristics Related to Abolition of AHR After Benralizumab and Dupilumab?

open access: yes
Clinical &Experimental Allergy, EarlyView.
Philipp Suter   +3 more
wiley   +1 more source

Lipid Metabolism and Obesity in Early Life: Drivers of Chronic Lung Disease From Development to Adulthood

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 7, 15 April 2026.
Metabolic and nutritional stressors are a growing global health concern. This review discusses how obesity, lipids, and lipid derivatives influence lung development, homeostasis, and chronic lung disease progression, highlighting roles of alveolar surfactant and sphingolipids.
Jaco Selle   +8 more
wiley   +1 more source

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