Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse [PDF]
Background It has been proposed that serotonin (5-HT)-mediated constriction of the murine trachea is largely dependent on acetylcholine (ACh) released from the epithelium.
Koepsell Hermann+8 more
doaj +5 more sources
Management of Exercise-Induced Bronchoconstriction [PDF]
Exercise-induced bronchoconstriction (EIB) is a common clinical manifestation of asthma, occurring in 70% to 80% of asthmatics. Evidence suggests that exercise and the ensuing bronchoconstriction do not contribute to a worsening of asthmatic inflammation.
Mark D Inman
doaj +4 more sources
Excipients of inhaled medications with potential to cause adverse reactions [PDF]
Introduction: In addition to the active pharmaceutical ingredient (API), the composition of the medicines also includes excipients which are only ideally completely pharmacologically inactive. It has been shown that excipients in inhaled preparations can
Kusonić Dejan Ž.+7 more
doaj +1 more source
The Aftermath of Bronchoconstriction [PDF]
Asthma is characterized by chronic airway inflammation, airway remodeling, and excessive constriction of the airway. Detailed investigation exploring inflammation and the role of immune cells has revealed a variety of possible mechanisms by which chronic inflammation drives asthma development.
Michael O'Sullivan, Bo Lan
openaire +3 more sources
Bronchoconstriction following instillation of phenylephrine eye drops in premature infants with bronchopulmonary dysplasia: two cases report [PDF]
Premature infants requiring an ophthalmic examination or even surgery for retinopathy of prematurity (ROP) have a high prevalence of co-existing bronchopulmonary dysplasia (BPD). Reactive airway is one of the clinical presentations of BPD.
Hyun Jee Kim+2 more
doaj +1 more source
Bronchoconstriction: a potential missing link in airway remodelling [PDF]
In asthma, progressive structural changes of the airway wall are collectively termed airway remodelling. Despite its deleterious effect on lung function, airway remodelling is incompletely understood.
Michael J. O'Sullivan+2 more
doaj +1 more source
Abstract The role of the calcium‐sensitive receptor (CaSR) was assessed in a juvenile mouse model of asthma induced by ovalbumin (OVA). The experiment was divided into normal control, OVA, and OVA +2.5/5 mg/kg NPS2143 (a CaSR antagonist) groups.
Zhao‐Yan Xiang, Di‐Di Tao
wiley +1 more source
Mechanosensitive vagal afferents in the lung, rapidly and slowly adapting receptors (RARs and SARs, respectively), play an important role in eliciting the reflexes that regulate the normal airway function.
You Shuei Lin+5 more
doaj +1 more source
Peculiarities of Airway Inflammation and Lipid Peroxidation in the Development of Hyperosmotic Airway Hyperresponsiveness in Patients with Asthma [PDF]
The aim of our study was to evaluate the role of airway cellular inflammation and the lipid peroxidation level in the development of airway hyperresponsiveness (AHR) to inhalation of hypertonic saline (IHS).
Alexey B. Pirogov+6 more
doaj +1 more source
Prevalence of exercise‐induced bronchoconstriction and laryngeal obstruction in adolescent athletes
To study the prevalence of exercise‐induced bronchoconstriction (EIB) and exercise‐induced laryngeal obstruction (EILO) in adolescent athletes.
K. Ersson+5 more
semanticscholar +1 more source