Results 131 to 140 of about 61,454 (303)

Effects of the P2RX4 antagonist BR11595 in a guinea pig model of chronic asthma

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 21, Page 5378-5390, November 2025.
Abstract Background and Purpose Asthma is characterized by airway hyperresponsiveness (AHR), allergic inflammation, and airway remodelling. Although recent studies have shown that asthma pathophysiology involves P2X4 receptor activation, a potential link with chronic asthma remains to be explored.
Dan Li   +13 more
wiley   +1 more source

Survey on 9 years of anti‐doping controls in horse races in Italy

open access: yesEquine Veterinary Journal, Volume 57, Issue 6, Page 1592-1599, November 2025.
Abstract Background Doping in racehorses is a threat to horse welfare and the integrity of the sport. Despite its relevance, the literature on the prevalence of anti‐doping violations worldwide is limited. Objectives To analyse anti‐doping violations in racehorses in Italy. Study Design Retrospective observational study.
Mariana Roccaro   +5 more
wiley   +1 more source

Multicomponent Synthesis of Fluorine‐Containing Bioactive Compounds and Drugs

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 38, October 15, 2025.
Multicomponent reactions are robust synthetic tools to assamble complex polyheterocycles and other interesting molecular architectures with potential application in medicinal chemistry, including their fluorine‐containing analogues. Fluorine atoms placed strategically into bioactive molecules often enhance essential pharmacokinetic parameters like ...
Ivette Morales‐Salazar   +7 more
wiley   +1 more source

Efficacy and safety of glycopyrrolate in patients with COPD by reversibility: pooled analysis of the GEM1 and GEM2 12-week studies

open access: yesInternational Journal of COPD, 2019
Jill A Ohar,1 Alyssa Bowling,2 Thomas Goodin,2 Barry Price,2 Ayca Ozol-Godfrey,2 Sanjay Sharma,2 Shahin Sanjar2 1Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA; 2Sunovion Pharmaceuticals Inc, Marlborough, MA, USA
Ohar JA   +6 more
doaj  

Clinical Pharmacology of Bronchodilator Medications

open access: yesRespiratory care, 2018
Dennis Williams, B. Rubin
semanticscholar   +1 more source

Kartagener's Syndrome With Complications: Diagnostic Challenges in a Resource‐Limited Setting

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Kartagener's Syndrome (KS) is a rare genetic disorder characterized by bronchiectasis, chronic sinusitis, and situs inversus. This case report presents a 14‐year‐old girl from rural Bangladesh diagnosed with KS, who exhibited progressive respiratory distress, recurrent sinus infections, and primary amenorrhea.
Nahid Afsar   +4 more
wiley   +1 more source

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