Results 71 to 80 of about 61,454 (303)

Acute bronchitis: challenges of diagnosis and treatment

Медицинский совет, 2013
Internal medicine specialists often have difficulty in making diagnosis and defining the type of treatment for patients with first time long-lasting cough or newly developed bronchial obstruction syndrome. Acute bronchitis (AB) is one of reasons of cough
I. V. Leschenko
doaj   +1 more source

Role of Forced Expiratory Volume in Third second (FEV3) as An Alternative to Forced Vital Capacity (FVC) in Assessing Bronchodilator Response in Patients with Chronic Obstructive Airway Diseases

The Iraqi Journal of Medical Sciences, 2020
Background: Spirometry is a physiological procedure used as a diagnostic tool for disease diagnosis; e.g. obstructive pulmonary diseases such as asthma or chronic obstructive pulmonary disease (COPD).
Alaa Jizar, Zeinab Hashim, Ahmed Jasim
doaj   +1 more source

Remote Monitoring of Inhaled Bronchodilator Use and Weekly Feedback about Asthma Management: An Open-Group, Short-Term Pilot Study of the Impact on Asthma Control

PLoS ONE, 2013
Objective Adequate symptom control is a problem for many people with asthma. We asked whether weekly email reports on monitored use of inhaled, short-acting bronchodilators might improve scores on composite asthma-control measures.
D. Van Sickle, S. Magzamen, S. Truelove, T. Morrison   +3 more
semanticscholar   +1 more source

A genome-wide association study of bronchodilator response in asthmatics

The Pharmacogenomics Journal, 2013
Reversibility of airway obstruction in response to β2-agonists is highly variable among asthmatics, which is partially attributed to genetic factors. In a genome-wide association study of acute bronchodilator response (BDR) to inhaled albuterol, 534 290 ...
Q. Duan, J. Lasky-Su, B. Himes, W. Qiu, A. Litonjua, A. Damask, R. Lazarus, B. Klanderman, C. Irvin, S. Peters, J. Hanrahan, J. Lima, F. Martinez, D. Mauger, V. Chinchilli, M. Soto-Quiros, L. Avila, J. Celedón, C. Lange, S. Weiss, K. Tantisira   +20 more
semanticscholar   +1 more source

Predictors of Response to Biologics for Severe Asthma: A Systematic Review and Meta‐Analysis

Allergy, EarlyView.
ABSTRACT Biologics are effective for severe asthma, but not all patients benefit equally. There is an urgent need to understand which biologic works best for which patient. We systematically searched for predictors of response to biologics (except omalizumab) for severe asthma in four bibliographic databases and two trial registries from 1990 to 2024 ...
Anna Rattu, Piers Dixey, David Charles, Chris Brightling, Kian Fan Chung, Apostolos Bossios, Arnaud Bourdin, Ratko Djukanovic, Sven‐Erik Dahlén, Louise Fleming, Rekha Chaudhuri, Erik Melén, Antoine Deschildre, Charles Pilette, Gerard H. Koppelman, Andrew Exley, Freja Anckers, Sarah Miller, Hanna Nielsen, Clare Williams, Ekaterina Khaleva, Graham Roberts, on behalf of the 3TR consortium Respiratory Work Package   +22 more
wiley   +1 more source

Randomized dose-finding study of batefenterol via dry powder inhaler in patients with COPD

International Journal of COPD, 2019
Courtney Crim,1 Michael L Watkins,1 Eric D Bateman,2 Gregory J Feldman,3 Isabelle Schenkenberger,4 Edward M Kerwin,5 Catriona Crawford,6 Krishna Pudi,7 Shuyen Ho,8 Charlotte Baidoo,9 Ramiro Castro-Santamaria10 1GSK, Research and Development, Research ...
Crim C, Watkins ML, Bateman ED, Feldman GJ, Schenkenberger I, Kerwin EM, Crawford C, Pudi K, Ho S, Baidoo C, Castro-Santamaria R   +10 more
doaj  

‘The blue one takes a battering’ why do young adults with asthma overuse bronchodilator inhalers? A qualitative study

BMJ Open, 2013
Objective Overuse of short-acting bronchodilators is internationally recognised as a marker of poor asthma control, high healthcare use and increased risk of asthma death. Young adults with asthma commonly overuse short-acting bronchodilators.
S. Cole, C. Seale, C. Griffiths
semanticscholar   +1 more source

Effect of the Arg16Gly β2‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

Allergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco, Evelina Fagone, Raffaele Campisi, Andrea Portacci, Giulia Scioscia, Corrado Pelaia, Angelantonio Maglio, Claudio Candia, Vitaliano Nicola Quaranta, Isabella Carrieri, Alessandro Saglia, Alessandro Vatrella, Girolamo Pelaia, Carlo Vancheri, Maria Pia Foschino Barbaro, Maria D'Amato, Giovanna Elisiana Carpagnano, Nunzio Crimi, Claudia Crimi, on behalf of the Southern Italy Network on Severe Asthma Therapy, Rossella Intravaia, Morena Porto, Pietro Impellizzeri, Maria Provvidenza Pistorio, Fabio Vignera, Andrea Alessia Nardo, Concetta Giannì, Silvano Dragonieri, Flogerta Sana, Valeria Pezzuto, Santina Ferulli, Massimo Triggiani, Roberta Parente, Pasquale Tondo, Piera Soccio, Donato Lacedonia, Luigi Ciampo, Antonio Franzese, Valeria Longobardi   +38 more
wiley   +1 more source

Efficacy and safety of twice-daily glycopyrrolate in patients with stable, symptomatic COPD with moderate-to-severe airflow limitation: the GEM1 study

International Journal of COPD, 2016
Craig LaForce,1 Gregory Feldman,2 Selwyn Spangenthal,3 Joerg H Eckert,4 Michelle Henley,5 Francesco Patalano,4 Peter D’Andrea5 1North Carolina Clinical Research, Raleigh, NC, USA; 2South Carolina Pharmaceutical Research, Spartanburg, SC, USA ...
LaForce C, Feldman G, Spangenthal S, Eckert JH, Henley M, Patalano F, D’Andrea P   +6 more
doaj  

Long‐Term, Real‐World Effectiveness of Allergen Immunotherapy in Children and Adolescents With Allergic Rhinitis and Asthma

Allergy, EarlyView.
Pre‐defined, propensity score–matched paediatric cohort from REACT evaluating the long‐term effectiveness of AIT in children with AR, with or without asthma. AIT‐treated children showed greater reductions in AR medication use, asthma medication use, severe asthma exacerbations, and new oral corticosteroid prescriptions versus controls over 9 years ...
Christian Woehlk, Thomas Stranzl, Marco Contoli, Nick Freemantle, Andreas Kallsoy Slaettanes, Julie Rask Larsen, Celeste Porsbjerg, Benedikt Fritzsching   +7 more
wiley   +1 more source