Results 81 to 90 of about 62,270 (271)

Dynamic confidence during simulated clinical tasks [PDF]

open access: yes, 2005
Objective: Doctors' confidence in their actions is important for clinical performance. While static confidence has been widely studied, no study has examined how confidence changes dynamically during clinical tasks.
Blagrove, M., Byrne, A., McDougall, S.
core   +2 more sources

Prevalence and Spirometric Transitions of PRISm and Obstruction: A Population‐Based Study

open access: yesRespirology, EarlyView.
ABSTRACT Background and Objective This study aims to assess the prevalence and longitudinal transitions of spirometric patterns defined by the lower limit of normal (LLN) criteria: normal airflow (FEV1/FVC≥LLN, FEV1 ≥ LLN); preserved ratio impaired spirometry (PRISm; FEV1/FVC≥LLN, FEV1 < LLN); or obstruction (FEV1/FVC
Charmaine J. M. Lim   +7 more
wiley   +1 more source

Randomized dose-finding study of batefenterol via dry powder inhaler in patients with COPD

open access: yesInternational Journal of COPD, 2019
Courtney Crim,1 Michael L Watkins,1 Eric D Bateman,2 Gregory J Feldman,3 Isabelle Schenkenberger,4 Edward M Kerwin,5 Catriona Crawford,6 Krishna Pudi,7 Shuyen Ho,8 Charlotte Baidoo,9 Ramiro Castro-Santamaria10 1GSK, Research and Development, Research ...
Crim C   +10 more
doaj  

Measurement of environmental tobacco smoke exposure among adults with asthma. [PDF]

open access: yes, 2001
Because the morbidity and mortality from adult asthma have been increasing, the identification of modifiable environmental exposures that exacerbate asthma has become a priority. Limited evidence suggests that exposure to environmental tobacco smoke (ETS)
Blanc, PD   +4 more
core   +2 more sources

Can Patient Education Lead the Way? Head‐To‐Head Comparison of EXACT and CERT for Early Recognition of Acute COPD Exacerbations

open access: yesRespirology, EarlyView.
Daily head‐to‐head comparison of EXACT vs. CERT for early detection of acute COPD exacerbations. Both tools accurately identified exacerbations at diagnosis (AUC≈0.9), but CERT detected worsening one day earlier (p = 0.006). CERT's simplicity and free access support rapid patient self‐monitoring and may enable timely intervention.
Rainer Gloeckl   +9 more
wiley   +1 more source

Efficacy and safety of twice-daily glycopyrrolate in patients with stable, symptomatic COPD with moderate-to-severe airflow limitation: the GEM1 study

open access: yesInternational Journal of COPD, 2016
Craig LaForce,1 Gregory Feldman,2 Selwyn Spangenthal,3 Joerg H Eckert,4 Michelle Henley,5 Francesco Patalano,4 Peter D’Andrea5 1North Carolina Clinical Research, Raleigh, NC, USA; 2South Carolina Pharmaceutical Research, Spartanburg, SC, USA ...
LaForce C   +6 more
doaj  

Transforming acute exacerbations of chronic obstructive pulmonary disease (AECOPD) risk assessment: A multi‐algorithm machine learning approach for precise clinical phenotyping

open access: yesVIEW, EarlyView.
We addressed the clinical need for individualized early identification of AECOPD by analyzing a longitudinal cohort of 878 COPD patients (20072024) and benchmarking 91 algorithms, yielding an interpretable ensemble model (AECOPD‐RS). The model showed strong performance (C‐index 0.815; validation 1/3/5‐year AUCs 0.864/0.865/0.855), with SHAP/VIMP ...
Yiqun Dong   +5 more
wiley   +1 more source

Risk factors for acute exacerbations of COPD in a primary care population: A retrospective observational cohort study [PDF]

open access: yes, 2014
Objectives: To evaluate risk factors associated with exacerbation frequency in primary care. Information on exacerbations of chronic obstructive pulmonary disease (COPD) has mainly been generated by secondary care-based clinical cohorts.
Hawkins, A   +3 more
core   +3 more sources

Complementary Predictors for Asthma Attack Prediction in Children: Salivary Microbiome, Serum Inflammatory Mediators, and Past Attack History

open access: yesAllergy, EarlyView.
In this two‐phase study, school‐aged children were classified as at risk or no‐risk based on severe attacks during one‐year follow‐up. Four types of prediction models were developed. Salivary bacteria and serum inflammatory markers, while informative alone, complement past asthma attacks in predicting future attack risk.
Shahriyar Shahbazi Khamas   +59 more
wiley   +1 more source

Exacerbations of COPD

open access: yesInternational Journal of COPD, 2016
Ian D Pavord,1 Paul W Jones,2 Pierre-Régis Burgel,3 Klaus F Rabe4,5 1Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK; 2Division of Clinical Science, St George’s, University of London, London, UK;
Pavord ID, Jones PW, Burgel PR, Rabe KF
doaj  

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