Results 91 to 100 of about 20,435 (278)

Effect of carbocisteine in prevention of exacerbation of chronic obstructive pulmonary disease (CAPRI study): an observational study [PDF]

open access: yes, 2016
Chronic Obstructive Pulmonary Disease (COPD) is a chronic and progressive lung disease characterized by irreversible airflow obstruction, airway inflammation , oxidative stress and, often, mucus hypersecretion.
BOCCHINO, MARIALUISA   +6 more
core   +1 more source

Survey on 9 years of anti‐doping controls in horse races in Italy

open access: yesEquine Veterinary Journal, Volume 57, Issue 6, Page 1592-1599, November 2025.
Abstract Background Doping in racehorses is a threat to horse welfare and the integrity of the sport. Despite its relevance, the literature on the prevalence of anti‐doping violations worldwide is limited. Objectives To analyse anti‐doping violations in racehorses in Italy. Study Design Retrospective observational study.
Mariana Roccaro   +5 more
wiley   +1 more source

A Delphi Consensus Document on the Use of Single-Inhaler Fixed-Dose Triple Therapies in COPD Patients

open access: yesInternational Journal of COPD, 2020
José Luis López-Campos,1,2 Bernardino Alcázar Navarrete,3 Juan Antonio Riesco Miranda,2,4 Borja G Cosío,2,5 Juan P de-Torres,6 Bartolomé Celli,7 Carlos A Jiménez-Ruiz,8 Ciro Casanova Macario9 1Unidad Mé ...
López-Campos JL   +7 more
doaj  

COPD: Optimizing Treatment [PDF]

open access: yes, 2015
A guideline update and an expanded armamentarium have many physicians wondering how best to treat patients with COPD. Chronic obstructive pulmonary disease (COPD) carries a high disease burden. In 2012, it was the 4th leading cause of death worldwide.1,2
Ahmed-Sarwar, Nabila   +2 more
core   +1 more source

Multicomponent Synthesis of Fluorine‐Containing Bioactive Compounds and Drugs

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 38, October 15, 2025.
Multicomponent reactions are robust synthetic tools to assamble complex polyheterocycles and other interesting molecular architectures with potential application in medicinal chemistry, including their fluorine‐containing analogues. Fluorine atoms placed strategically into bioactive molecules often enhance essential pharmacokinetic parameters like ...
Ivette Morales‐Salazar   +7 more
wiley   +1 more source

The clinical effectiveness and cost-effectiveness of inhaler devices used in the routine management of chronic asthma in older children: a systematic review and economic evaluation [PDF]

open access: yes, 2002
Background: This review examines the clinical effectiveness and cost-effectiveness of hand-held inhalers to deliver medication for the routine management of chronic asthma in children aged between 5 and 15 years.
Beverley, C.   +4 more
core   +1 more source

Expanding the Spectrum: A Rare Case of Morquio Syndrome With Bronchial Asthma and Seizure Disorder

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT This case highlights a rare co‐existence of Morquio syndrome with bronchial asthma and myoclonic seizures, expanding the known clinical spectrum. It emphasizes the need for comprehensive, multidisciplinary management to address multisystem involvement and describes the challenges of treatment in resource‐limited settings where advanced ...
Bijay Bastola   +4 more
wiley   +1 more source

Inhaler Devices for Delivery of LABA/LAMA Fixed-Dose Combinations in Patients with COPD

open access: yesPulmonary Therapy, 2019
Inhaled fixed-dose combinations (FDCs) of a long-acting β-agonist (LABA) and a long-acting muscarinic antagonist (LAMA) have become the cornerstone for the maintenance treatment of symptomatic COPD patients.
Anthony D’Urzo   +5 more
doaj   +1 more source

Beta(2)-adrenergic receptor (ADRB2) gene polymorphisms and risk of COPD exacerbations : the Rotterdam study [PDF]

open access: yes, 2019
The role of the beta(2)-adrenergic receptor (ADRB2) gene in patients with chronic obstructive pulmonary disease (COPD) is unclear. We investigated the association between ADRB2 variants and the risk of exacerbations in COPD patients treated with inhaled ...
Brusselle, Guy   +8 more
core   +2 more sources

The Impact of Climatic Factors on Respiratory Pharmaceutical Demand: A Comparison of Forecasting Models for Greece

open access: yesEnvironmetrics, Volume 36, Issue 7, October 2025.
ABSTRACT Climate change is increasingly recognized as a driver of health‐related outcomes, yet its impact on pharmaceutical demand remains largely understudied. As environmental conditions evolve and extreme weather events intensify, anticipating their influence on medical needs is essential for designing resilient healthcare systems.
Viviana Schisa, Matteo Farnè
wiley   +1 more source

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