COPD and glycopyrronium responsiveness assessment: An appraisal
Clinical Trial Registration: ECR/159/Inst/WB/2013/RR-20 Background: Glycopyrronium bromide (a long-acting antimuscarinic agent: LAMA) appears pharmacokinetically suitable for testing bronchodilator responsiveness as salbutamol (short-acting β2-agonist ...
Parthasarathi Bhattacharyya+5 more
doaj +1 more source
An update on the use of indacaterol in patients with COPD
Current guidelines for the management of chronic obstructive pulmonary disease (COPD) establish that bronchodilator medications are central to the symptomatic treatment of the disease.
Nadia S. Brienza+2 more
doaj +1 more source
Beta-2 agonists for the treatment of bronchiolitis
INTRODUCCIÓN La bronquiolitis es la inflamación aguda de las vías aéreas de pequeño calibre, teniendo como causa principal las infecciones virales. Es altamente frecuente en menores de dos años, sobretodo en menores de 12 meses. Existe gran controversia
Constanza Gómez+2 more
doaj +1 more source
Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD [PDF]
Objective We performed a review of studies of fluticasone propionate (FP)/salmeterol (SAL) (combination inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA)) in patients with COPD, which measured baseline (pretreatment) blood eosinophil levels, to ...
Barnes, NC+6 more
core +1 more source
Improving of Robotic Virtual Agent's errors that are accepted by reaction and human's preference [PDF]
One way to improve the relationship between humans and anthropomorphic agents is to have humans empathize with the agents. In this study, we focused on a task between an agent and a human in which the agent makes a mistake. To investigate significant factors for designing a robotic agent that can promote humans empathy, we experimentally examined the ...
arxiv
Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events [PDF]
An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in previous Cochrane reviews.ObjectivesWe set out to compare the risks of mortality and non-fatal serious adverse events in ...
Altman+18 more
core +1 more source
Pharmacologic Therapies for Preventing Chronic Obstructive Pulmonary Disease Exacerbations: A Comprehensive Review [PDF]
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by acute exacerbations that accelerate disease progression, increase hospitalizations, and elevate mortality.
Hyun Woo Lee
doaj +1 more source
Beta(2)-adrenergic receptor (ADRB2) gene polymorphisms and risk of COPD exacerbations : the Rotterdam study [PDF]
The role of the beta(2)-adrenergic receptor (ADRB2) gene in patients with chronic obstructive pulmonary disease (COPD) is unclear. We investigated the association between ADRB2 variants and the risk of exacerbations in COPD patients treated with inhaled ...
Brusselle, Guy+8 more
core +2 more sources
Cooperative and Competitive Biases for Multi-Agent Reinforcement Learning [PDF]
Training a multi-agent reinforcement learning (MARL) algorithm is more challenging than training a single-agent reinforcement learning algorithm, because the result of a multi-agent task strongly depends on the complex interactions among agents and their interactions with a stochastic and dynamic environment.
arxiv
Regular treatment with formoterol for chronic asthma: serious adverse events [PDF]
Epidemiological evidence has suggested a link between beta(2)-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are safe ...
Altman+17 more
core +1 more source