Pharmacologic Therapies for Preventing Chronic Obstructive Pulmonary Disease Exacerbations: A Comprehensive Review [PDF]
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by acute exacerbations that accelerate disease progression, increase hospitalizations, and elevate mortality.
Hyun Woo Lee
doaj +1 more source
COPD and glycopyrronium responsiveness assessment: An appraisal
Clinical Trial Registration: ECR/159/Inst/WB/2013/RR-20 Background: Glycopyrronium bromide (a long-acting antimuscarinic agent: LAMA) appears pharmacokinetically suitable for testing bronchodilator responsiveness as salbutamol (short-acting β2-agonist ...
Parthasarathi Bhattacharyya +5 more
doaj +1 more source
A combination of long-acting anticholinergic agents (LAACs) and long-acting &bgr;2-adrenergic receptor agonist (LABA) is effective in improving lung function in chronic obstructive pulmonary disease (COPD) compared with monotherapy.
M. Tsai +6 more
semanticscholar +1 more source
Combination formoterol and inhaled steroid versus beta(2)-agonist as relief medication for chronic asthma in adults and children (Review) [PDF]
Background Formoterol has a fast onset of action and can therefore be used to relieve symptoms of asthma. A combination inhaler can deliver formoterol with different doses of inhaled corticosteroid; when used as a reliever both drugs will be delivered ...
Adams +46 more
core +1 more source
Overprescription of short-acting β2 agonists: reflections from the SABINA study in Brazil
Objective: To assess prescription patterns for short-acting b2 agonists (SABAs) and other asthma medications in asthma patients treated by specialists and participating in the SABA use IN Asthma (SABINA) study in Brazil.
Martti Anton Antila +7 more
doaj +2 more sources
Adherence to Inhalation Devices in Patients with Chronic Obstructive Pulmonary Disease
Luis Fernando Valladales-Restrepo,1– 3 María Camila Oyuela-Gutiérrez,3 Ana Camila Delgado-Araujo,1 Juliana Calvo-Salazar,1 Daniel Osorio-Bustamante,3 Cesar Eduardo Lerma-Barco,3 Jorge Enrique Machado-Alba1 1Grupo de Investigación en Farmacoepidemiología ...
Valladales-Restrepo LF +6 more
doaj
Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD [PDF]
Objective We performed a review of studies of fluticasone propionate (FP)/salmeterol (SAL) (combination inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA)) in patients with COPD, which measured baseline (pretreatment) blood eosinophil levels, to ...
Barnes, NC +6 more
core +1 more source
Short-acting β2-agonist prescriptions in patients with asthma: findings from the South Korean cohort of SABINA III [PDF]
Background/Aims Despite short-acting β2-agonist (SABA) overuse being associated with poor asthma outcomes, data on SABA use in South Korea is scarce.
Kwang-Ha Yoo +6 more
doaj +1 more source
Structure and Dynamics of the M3 Muscarinic Acetylcholine Receptor
Acetylcholine, the first neurotransmitter to be identified, exerts many of its physiological actions via activation of a family of G-protein-coupled receptors (GPCRs) known as muscarinic acetylcholine receptors (mAChRs). Although the five mAChR subtypes (
A. Kruse +13 more
semanticscholar +1 more source
The role of bronchodilator treatment in the prevention of exacerbations of COPD
Exacerbations of chronic obstructive pulmonary disease (COPD) are natural events in the progression of the disease, and are characterised by acute worsening of symptoms, especially dyspnoea. These heterogeneous events follow increased airway inflammation,
J. Wedzicha, M. Decramer, T. Seemungal
semanticscholar +1 more source

