Results 31 to 40 of about 3,193,785 (231)
Novel small airway bronchodilator responses to rosiglitazone in mouse lung slices.
There is a need to identify novel agents that elicit small airway relaxation when β2-adrenoceptor agonists become ineffective in difficult-to-treat asthma.
J. Bourke+5 more
semanticscholar +1 more source
Manuel Enrique Machado-Duque,1,2 Andrés Gaviria-Mendoza,1,2 Luis Fernando Valladales-Restrepo,1,2 Andrés González-Rangel,3 Maria Eugenia Laucho-Contreras,3,4 Jorge Enrique Machado-Alba1 1Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia,
Machado-Duque ME+5 more
doaj
Structure and Dynamics of the M3 Muscarinic Acetylcholine Receptor
Acetylcholine, the first neurotransmitter to be identified, exerts many of its physiological actions via activation of a family of G-protein-coupled receptors (GPCRs) known as muscarinic acetylcholine receptors (mAChRs). Although the five mAChR subtypes (
A. Kruse+13 more
semanticscholar +1 more source
The role of bronchodilator treatment in the prevention of exacerbations of COPD
Exacerbations of chronic obstructive pulmonary disease (COPD) are natural events in the progression of the disease, and are characterised by acute worsening of symptoms, especially dyspnoea. These heterogeneous events follow increased airway inflammation,
J. Wedzicha, M. Decramer, T. Seemungal
semanticscholar +1 more source
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves+3 more
wiley +1 more source
The Development and Challenges of PET/MRI Dual‐Modality Imaging Probes—An Update
ABSTRACT The integration of Positron emission tomography (PET) with Magnetic resonance imaging (MRI) combines the functional imaging capabilities of PET with the high‐resolution anatomical detail of MRI, creating a synergistic platform for advanced diagnostic imaging and image‐guided therapies. Central to the success of this dual‐modality system is the
Maryam Sabbaghan+5 more
wiley +1 more source
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo+5 more
wiley +1 more source
openalex +2 more sources
This study systematically reviews essential oil (EO) profiles of Lippia turbinata (Verbenaceae) populations from Argentina. A meta‐analysis reveals significant chemical variability and distinct chemotypes, primarily defined by limonene, carvone, β‐caryophyllene, and caryophyllene oxide.
Fernando Livio Corzo+4 more
wiley +1 more source
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang+4 more
wiley +1 more source