Results 111 to 120 of about 1,141,798 (294)
Experimental and Molecular Medicine, 2019 Fat tissue disorders: Dysfunctional fat cell differentiation An abnormal distribution of fatty tissues associated with certain tissue disorders is driven by disrupted fat cell differentiation.
Camilla Pellegrini +17 more
doaj +1 more source
Highly Selective In Vivo Labeling of Subcutaneous White Adipocyte Precursors with Prx1-Cre
Stem Cell Reports, 2015 The origins of individual fat depots are not well understood, and thus, the availability of tools useful for studying depot-specific adipose tissue development and function is limited.
Joan Sanchez-Gurmaches +2 more
doaj +1 more source
Biology of Beige Adipocyte and Possible Therapy for Type 2 Diabetes and Obesity
International Journal of Endocrinology, 2016 All mammals own two main forms of fat. The classical white adipose tissue builds up energy in the form of triglycerides and is useful for preventing fatigue during periods of low caloric intake and the brown adipose tissue instead of inducing fat ...
Fernando Lizcano, Diana Vargas
doaj +1 more source
Perivascular adipose tissue inflammation in vascular disease [PDF]
, 2017 Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
core +1 more source
Essential role for miR-196a in brown adipogenesis of white fat progenitor cells.
PLoS Biology, 2012 The recent discovery of functional brown adipocytes in adult humans illuminates the potential of these cells in the treatment of obesity and its associated diseases. In rodents, brown adipocyte-like cells are known to be recruited in white adipose tissue
Masaki Mori +4 more
doaj +1 more source
EBF2 Determines and Maintains Brown Adipocyte Identity [PDF]
Cell Metabolism, 2013 The master transcription factor Pparγ regulates the general differentiation program of both brown and white adipocytes. However, it has been unclear whether Pparγ also controls fat lineage-specific characteristics. Here, we show that early B cell factor-2 (Ebf2) regulates Pparγ binding activity to determine brown versus white adipocyte identity.
Patrick Seale +7 more
openaire +3 more sources
GRAF1 deficiency leads to defective brown adipose tissue differentiation and thermogenic response
Scientific ReportsAdipose tissue, which is crucial for the regulation of energy within the body, contains both white and brown adipocytes. White adipose tissue (WAT) primarily stores energy, while brown adipose tissue (BAT) plays a critical role in energy dissipation as ...
Xue Bai +5 more
doaj +1 more source
COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA [PDF]
, 1993 Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway.
Lachmann, PJ +4 more
core +1 more source
Methyltransferase and demethylase profiling studies during brown adipocyte differentiation
BMB Reports, 2016 Although brown adipose tissue is important with regard to energy balance, the molecular mechanism of brown adipocyte differentiation has not been extensively studied.
Min Jeong Son +7 more
semanticscholar +1 more source
Zbtb16 has a role in brown adipocyte bioenergetics [PDF]
Nutrition & Diabetes, 2012 A better understanding of the processes influencing energy expenditure could provide new therapeutic strategies for reducing obesity. As the metabolic activity of the brown adipose tissue (BAT) and skeletal muscle is an important determinant of overall energy expenditure and adiposity, we investigated the role of genes that could influence cellular ...
Christopher L. Plaisier +7 more
openaire +3 more sources