Results 151 to 160 of about 1,154,949 (367)

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, EarlyView.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source

Coordinate Functional Regulation between Microsomal Prostaglandin E Synthase-1 (mPGES-1) and Peroxisome Proliferator-activated Receptor y (PPARy) in the Conversion of White-to-brown Adipocytes [PDF]

, 2017
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated nuclear receptor and a master regulator of adipogenesis. Microsomal prostaglandin E (PGE) synthase-1 (mPGES-1) is an inducible enzyme that couples with cyclooxygenase-2 for the ...
Arroyo, Vicente, Clària i Enrich, Joan, García-Alonso, Verónica, González Périz, Ana, López Vicario, Cristina, Morán-Salvador, Eva, Párrizas, Marcelina, Rius, Bibiana, Titos Rodríguez, Esther, Werz, Oliver   +9 more
core   +1 more source

The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix

eLife, 2015
Maintenance of energy homeostasis depends on the highly regulated storage and release of triacylglycerol primarily in adipose tissue, and excessive storage is a feature of common metabolic disorders.
David Barneda, Joan Planas-Iglesias, M. Gaspar, D. Mohammadyani, Sunil Prasannan, D. Dormann, G. Han, S. A. Jesch, G. Carman, V. Kagan, M. Parker, N. Ktistakis, J. Klein-Seetharaman, A. M. Dixon, S. Henry, M. Christian   +15 more
semanticscholar   +1 more source

Novel discovery of Averrhoa bilimbi ethanolic leaf extract in the stimulation of brown fat differentiation program in combating diet-induced obesity

BMC Complementary and Alternative Medicine, 2019
Background Brown adipocytes are known to promote energy expenditure and limit weight gain to combat obesity. Averrhoa bilimbi, locally called belimbing buluh (DBB), is mainly used as an ethnomedicine in the treatment of metabolic disorders including ...
Wai Kwan Lau, Nur Adelina Ahmad Noruddin, Abdul Hadi Ariffin, Muhd Zulkarnain Mahmud, Mohd Hasnan Mohd Noor, Azimah Amanah, Mohamad Faiz Hamzah, Zainuddin Zafarina   +7 more
doaj   +1 more source

Supplementary material from "Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model"

, 2021
Gao S, Yanyun Pan, Yu, Na, Bai, Ying, Rufeng Ma, Fangfang Mo, Jiacheng Zuo, Beibei Chen, Qiangqiang Jia, Dongwei Zhang, Jiaxian Liu, Guanjian Jiang, Sihua Gao   +12 more
openalex   +1 more source

Adipose-Derived Stromal Cells Attenuate Adipose Inflammation in Obesity through Adipocyte Browning and Polarization of M2 Macrophages

Mediators of Inflammation, 2019
Obesity is a metabolic condition associated with multiple health problems such as endocrine and metabolic dysfunction and chronic inflammation in adipose tissues.
Wen-Chao Zhang, Feng Qin, Xiao-Jun Wang, Zhi-Fei Liu, Lin Zhu, Ang Zeng, Ming-Zi Zhang, Nan-Ze Yu, Xiao Long   +8 more
doaj   +1 more source

Effects of exercise on brown and beige adipocytes

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019
Physical exercise leads to beneficial effects in numerous tissues and organ systems and offers protection against obesity and type 2 diabetes. Recent studies have investigated the role of exercise on brown adipose tissue (BAT) and white adipose tissue (WAT), and have indicated marked adaptations to each tissue with exercise.
Dewal, Revati S., Stanford, Kristin I.
openaire   +2 more sources

MCT1 and MCT4 Expression and Lactate Flux Activity Increase During White and Brown Adipogenesis and Impact Adipocyte Metabolism

Scientific Reports, 2017
Adipose tissue takes up glucose and releases lactate, thereby contributing significantly to systemic glucose and lactate homeostasis. This implies the necessity of upregulation of net acid and lactate flux capacity during adipocyte differentiation and ...
Charlotte C. Petersen, M. D. Nielsen, Elise S. Andersen, A. Basse, M. Isidor, Lasse K. Markussen, B. Viuff, I. H. Lambert, J. Hansen, S. Pedersen   +9 more
semanticscholar   +1 more source

Schisantherin A: Remodeling Gut Microbiota to Activate the Gut–Immune–Neural–Adipose Axis for Thermogenesis

iNew Medicine, EarlyView.
ABSTRACT The global obesity epidemic necessitates safe and effective strategies to enhance energy expenditure. Schisantherin A (Sin A), a lignan derived from Schisandra chinensis, has demonstrated metabolic benefits, yet its systemic mechanism remains unclear.
Ling Yin
wiley   +1 more source

Cellular uptake of soy-derived phytoestrogens in vitro and in human whole blood [PDF]

, 2008
Epidemiological studies comparing typical Western and traditional Eastern lifestyles indicate that dietary intake of soyderived phytoestrogens, including genistein, daidzein, and equol, may have significant health protective effects on hormone-dependent ...
Bracke, Marc, De Keukeleire, Denis, Depypere, Herman, Heyerick, Arne, Maubach, Julie   +4 more
core