Results 161 to 170 of about 1,154,949 (367)

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

Journal of Applied Toxicology, EarlyView.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt, Nathalie Struwe, Annika Jansson, Vesna Munic Kos, Maria Larsson, Jana M. Weiss   +5 more
wiley   +1 more source

Regulation of rat foetal lipogenesis in brown adipose tissue in vivo and in isolated brown adipocytes during the last day of, and after prolonged, gestation [PDF]

, 1987
Cesáreo Roncero, Mari Luz García‐Lorenzo, Manuel Benito   +2 more
openalex   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source

Impact of dietary ω3 polyunsaturated fatty acid supplementation on brown and brite adipocyte function[S]

Journal of Lipid Research, 2018
The recent characterization of functional brown adipose tissue in adult humans has opened new perspectives for regulation of energy expenditure with respect to obesity and diabetes.
R. Ghandour, Cécilia Colson, M. Giroud, Stefanie Maurer, Samah Rekima, G. Ailhaud, M. Klingenspor, E. Amri, D. Pisani   +8 more
semanticscholar   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

RNA-binding protein YBX3 promotes PPARγ-SLC3A2 mediated BCAA metabolism fueling brown adipogenesis and thermogenesis

Molecular Metabolism
Objective: Activating brown adipose tissue (BAT) thermogenesis is a promising approach to combat obesity and metabolic disorders. The post-transcriptional regulation of BAT thermogenesis mediated by RNA-binding proteins (RBPs) is still not fully ...
Lin-Yun Chen, Li-Wen Wang, Jie Wen, Jing-Dong Cao, Rui Zhou, Jin-Lin Yang, Ye Xiao, Tian Su, Yan Huang, Qi Guo, Hai-Yan Zhou, Xiang-Hang Luo, Xu Feng   +12 more
doaj   +1 more source

Involvement of mechano-sensitive Piezo1 channel in the differentiation of brown adipocytes [PDF]

, 2022
Manato Kenmochi, Satoko Kawarasaki, Satsuki Takizawa, Kazuhiko Okamura, Tsuyoshi Goto, Kunitoshi Uchida   +5 more
openalex   +1 more source

Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation.

Cell Metabolism, 2020
D. Blondin, S. Nielsen, Eline N. Kuipers, M. C. Severinsen, V. Jensen, S. Miard, N. Jespersen, S. Kooijman, M. Boon, M. Fortin, S. Phoenix, F. Frisch, B. Guérin, É. Turcotte, F. Haman, D. Richard, F. Picard, P. Rensen, C. Schéele, A. Carpentier   +19 more
semanticscholar   +1 more source

HOXA5 Suppresses NEK7‐Mediated Alveolar Epithelial Pyroptosis in Acute Lung Injury by Transcriptionally Inhibiting KAT2A

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang, Heng Fan, Qi Wang, Cheng‐Jie Jiang, Dan‐Hui Li, Ji‐Hui Ye   +5 more
wiley   +1 more source

Adipose Tissue in SARS‐CoV‐2 Viral Tropism, Viral Replication, and the Concept of a Viral Reservoir: An Update

Obesity, EarlyView.
Adipose tissue as a potential reservoir for and modifier of SARS‐CoV‐2 infection and its complications. Schematic demonstrating the differences in subcutaneous and visceral adipose tissue and infection capacity of SARS‐CoV‐2 with interplay between macrophages and adipocytes as target cells for viral tropism.
Liam Charles Maher, Paul M. Ryan, Noel M. Caplice   +2 more
wiley   +1 more source