Results 71 to 80 of about 1,141,798 (294)
Effects of glucocorticoids on human brown adipocytes [PDF]
Journal of Endocrinology, 2014 Clinical cases of glucocorticoid (GC) excess are characterized by increased fat mass and obesity through the accumulation of white adipocytes. The effects of GCs on growth and function of brown adipose tissue are unknown and may contribute to the negative energy balance observed clinically. This study aims to evaluate the effect of GCs on proliferation,
Barclay, Johanna L. +5 more
openaire +4 more sources
BATLAS: Deconvoluting Brown Adipose Tissue
Cell Reports, 2018 Summary: Recruitment and activation of thermogenic adipocytes have received increasing attention as a strategy to improve systemic metabolic control. The analysis of brown and brite adipocytes is complicated by the complexity of adipose tissue biopsies ...
Aliki Perdikari +25 more
doaj +1 more source
Regulation of tissue crosstalk by skeletal muscle-derived myonectin and other myokines. [PDF]
, 2012 The integrated control of animal physiology requires intimate tissue crosstalk, a vital task mediated by circulating humoral factors. As one type of these factors, adipose tissue-derived adipokines have recently garnered attention as important regulators
Seldin, Marcus M, Wong, G William
core +1 more source
Androgens and Hypertension in Men and Women: a Unifying View. [PDF]
, 2017 This review was designed to revaluate the androgen role on the mechanisms of hypertension and cardiovascular risks in both men and women. Sex steroids are involved in the regulation of blood pressure, but pathophysiological mechanism is not well ...
Carmina, E. 4. +4 more
core +1 more source
Regulation of glycolysis in brown adipocytes by HIF-1α [PDF]
Scientific Reports, 2017 AbstractBrown adipose tissue takes up large amounts of glucose during cold exposure in mice and humans. Here we report an induction of glucose transporter 1 expression and increased expression of several glycolytic enzymes in brown adipose tissue from cold-exposed mice.
Sally Winther +10 more
openaire +6 more sources
BCL6 regulates brown adipocyte dormancy to maintain thermogenic reserve and fitness
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance During exposure to environmental cold, brown adipocytes protect against hypothermia by generating heat (thermogenesis). In warm environments, brown adipocytes become inactive or dormant but still maintain their identity and thermogenic ...
V. Kutyavin, A. Chawla
semanticscholar +1 more source
Loss of MyoD Promotes Fate Transdifferentiation of Myoblasts Into Brown Adipocytes
EBioMedicine, 2017 Brown adipose tissue (BAT) represents a promising agent to ameliorate obesity and other metabolic disorders. However, the abundance of BAT decreases with age and BAT paucity is a common feature of obese subjects. As brown adipocytes and myoblasts share a
Chao Wang +7 more
doaj +1 more source
Scientific Reports, 2018 Activation of brown adipose tissue (BAT) contributes to total body energy expenditure through energy dissipation as heat. Activated BAT increases the clearance of lipids and glucose from the circulation, but how BAT accommodates large influx of multiple ...
N. Held +11 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2023 Brown adipocytes is a specialized fat cell that dissipates nutrient-derived chemical energy in the form of heat, instead of ATP synthesis. This unique feature provides a marked capacity for brown adipocyte mitochondria to oxidize substrates independent ...
Ji Suk Chang
doaj +1 more source
Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancy [PDF]
, 2017 Obesity increases preeclampsia risk. Adipose tissue inflammation may contribute to the clinical syndrome of pre-eclampsia. We compared adipose tissue macrophage infiltration and release of pro-inflammatory adipokines in pre-eclampsia and healthy ...
Bray, Jack +6 more
core +1 more source