Results 81 to 90 of about 1,141,798 (294)
Shades of brown: an introduction for the special focus issue of Adipocyte on “brown and beige/brite adipocytes” [PDF]
Adipocyte, 2016 The re-discovery of brown adipose tissue in humans has re-kindled enormous interest in the research of brown, and its related brown-like adipocytes, i.e., beige or brite adipocytes.
openaire +3 more sources
L‐rhamnose induces browning in 3T3‐L1 white adipocytes and activates HIB1B brown adipocytes [PDF]
IUBMB Life, 2018 AbstractInduction of the brown adipocyte‐like phenotype in white adipocytes (browning) is considered as a novel strategy to fight obesity due to the ability of brown adipocytes to increase energy expenditure. Here, we report that L‐rhamnose induced browning by elevating expression levels of beige‐specific marker genes, including Cd137, Cited1, Tbx1 ...
Minji Choi +5 more
openaire +2 more sources
NRF2 is essential for adaptative browning of white adipocytes
Redox Biology, 2023 White adipose tissue browning, defined by accelerated mitochondrial metabolism and biogenesis, is considered a promising mean to treat or prevent obesity-associated metabolic disturbances. We hypothesize that redox stress acutely leads to increased production of reactive oxygen species (ROS), which activate electrophile sensor nuclear factor erythroid ...
Marco Bauzá-Thorbrügge +7 more
openaire +4 more sources
Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels
Molecular Metabolism, 2021 Objective: Brown adipose tissue (BAT) is specialized in thermogenesis. The conversion of energy into heat in brown adipocytes proceeds via stimulation of β-adrenergic receptor (βAR)-dependent signaling and activation of mitochondrial uncoupling protein 1
Subramanian Senthivinayagam +20 more
doaj +1 more source
Browning of Adipocytes: A Potential Therapeutic Approach to Obesity
Nutrients, 2023 The increasing prevalence of overweight and obesity suggests that current strategies based on diet, exercise, and pharmacological knowledge are not sufficient to tackle this epidemic. Obesity results from a high caloric intake and energy storage, the latter by white adipose tissue (WAT), and when neither are counterbalanced by an equally high energy ...
Vittoria Schirinzi +3 more
openaire +4 more sources
Molecular MetabolismBesides its thermogenic capacity, brown adipose tissue (BAT) performs important secretory functions that regulate metabolism. However, the BAT microenvironment and factors involved in BAT homeostasis and adaptation to cold remain poorly characterized. We
Marina Agueda-Oyarzabal +15 more
doaj +1 more source
Molecular Metabolism, 2020 Objective: Understanding the mechanisms that control brown adipose tissue (BAT) mass and functionality is crucial for our understanding of how the disruption of energy homeostasis leads to obesity. Bernerdinali Seip Congenital Lipodystrophy (BSCL) type 2
Hongyi Zhou +4 more
doaj +1 more source
Dynamic regulation of genes involved in mitochondrial DNA replication and transcription during mouse brown fat cell differentiation and recruitment. [PDF]
PLoS ONE, 2009 BACKGROUND: Brown adipocytes are specialised in dissipating energy through adaptive thermogenesis, whereas white adipocytes are specialised in energy storage.
Maria Murholm +8 more
doaj +1 more source
Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation
Molecular Metabolism, 2017 Objective: Long noncoding RNAs (lncRNAs) are emerging as important regulators of diverse biological processes. Recent work has demonstrated that the inducible lncRNA Blnc1 stimulates thermogenic gene expression during brown and beige adipocyte ...
Lin Mi +4 more
doaj +1 more source
Identification of Biochemical Differences in White and Brown Adipocytes Using FTIR Spectroscopy
Applied Sciences, 2022 This study was conducted to investigate the developmental characteristics of adipocytes and to identify selectively white and brown adipocytes through Fourier transform infrared (FTIR) spectroscopy.
DongHyun Shon +3 more
doaj +1 more source