Results 211 to 220 of about 1,575,823 (250)

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

GFRAL is required to mediate changes in systemic metabolism in response to mitochondrial stress in brown adipose tissue. [PDF]

J Mol Med (Berl)
Sood A, Peterson J, Jena J, Challa V, Washburn C, Seeley RJ, Pereira RO.   +6 more
europepmc   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

PCB-126 exposure promotes brown adipose tissue dysfunction and metabolic inflexibility in mice. [PDF]

Sci Rep
Peixoto TC, Miranda CS, Teixeira AMR, Quitete FT, Teixeira AVS, Monteiro EB, Martins BC, de Castro Resende A, Martins FF, de Barros Mucci D, Daleprane JB.   +10 more
europepmc   +1 more source

Trends and Approaches in Obesity and Overweight Research Focused on White Adipose Tissue and Browning: A Bibliometric Study

Obesity Reviews, EarlyView.
ABSTRACT The global rise in obesity has intensified scientific interest in adipose tissue biology, particularly the mechanisms underlying white adipose tissue (WAT) browning. This bibliometric study mapped the evolution, structure, and emerging directions of research on obesity, overweight, and WAT browning from 2011 to May 2025. Records were retrieved
Violeta Heras, Daniel Hinojosa‐Nogueira, Francisco J. Tinahones, Isabel Moreno‐Indias   +3 more
wiley   +1 more source

ACLY Safeguards Copper Homeostasis to Sustain Brown Adipose Tissue Thermogenesis and Restrain Diet-Induced Obesity. [PDF]

Research (Wash D C)
Liu X, Jia L, Li L, Huang J, Hou M, Li Z, Yao D, Yang Y, Wang J, Dai L.   +9 more
europepmc   +1 more source

Soft‐Tissue Keratocyst: A Report of Two New Cases

Oral Surgery, EarlyView.
ABSTRACT Background Soft‐tissue keratocyst (STKC) is an extremely rare lesion whose histogenesis, nomenclature, and biological characterization remain uncertain, largely due to its close morphological similarity to intraosseous odontogenic keratocyst and its completely extragnathic location.
Lucas Fabian Polti, Nayara Conceição Marcos Santana, María Cassia Ferreira Aguiar, Júlio César Tanos Lacerda, Renata Resende, Wagner Henriques Castro, Silvia Ferreira de Sousa, Felipe Paiva Fonseca, Ricardo Alves Mesquita   +8 more
wiley   +1 more source

Acyl-CoA Binding Protein in White and Brown Adipose Tissue Is Dispensable for Systemic Energy Metabolism in Mice. [PDF]

Acta Physiol (Oxf)
Nørremark MF, Petersen R, Ruppert PMM, Jul ES, Doktor TK, Nielsen R, Kappel JF, Larsen S, Kornfeld JW, Mandrup S, Andresen BS, Havelund J, Neess D, Færgeman NJ.   +13 more
europepmc   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Brown Adipose Tissue and Metabolic Markers Differ Between Greenlanders and Danes With Cold Activation.

J Clin Endocrinol Metab
Motzfeldt Jensen M, Almasi CE, Kjærgaard B, Rasmussen BS, Andersen MK, Schubert M, Hansen T, Ellervik C, Schéele C, Jørgensen ME, Andersen S.   +10 more
europepmc   +1 more source