Results 361 to 370 of about 1,390,341 (404)
Some of the next articles are maybe not open access.
2010
Brown adipose tissue is structurally and functionally different from white adipose tissue. Although abundant at birth, in the adult it exists only as small depots at specific locations such as the interscapular region of rodents. The brown colour of the tissue is due to an abundance of mitochondria.
Jürgen Roth, Margit Pavelka
openaire +2 more sources
Brown adipose tissue is structurally and functionally different from white adipose tissue. Although abundant at birth, in the adult it exists only as small depots at specific locations such as the interscapular region of rodents. The brown colour of the tissue is due to an abundance of mitochondria.
Jürgen Roth, Margit Pavelka
openaire +2 more sources
Brown adipose tissue functions in humans
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2013Human adults have functionally active BAT. The metabolic function can be reliably measured in vivo using modern imaging modalities (namely PET/CT). Cold seems to be one of the most potent stimulators of BAT metabolic activity but other stimulators (for example insulin) are actively studied.
Kirsi A. Virtanen +2 more
openaire +6 more sources
Bioenergenetics of brown adipose tissue
Lipids, 1970AbstractExamination of the effect of 2,4‐dinitrophenol (DNP) in vivo on the brown adipose tissue of cold‐exposed rats as well as the effect of DNP and dicumarol in vitro, indicates that brown fat does possess a functional electron transport‐coupled phosphorylating system.
R. E. Smith +2 more
openaire +3 more sources
The Genetics of Brown Adipose Tissue
2010Brown adipose tissue is highly differentiated and has evolved as a mechanism for heat production based upon uncoupling of mitochondrial oxidative phosphorylation. Additionally, large amounts of lipid can be stored in the cells to provide fuel necessary for heat production upon adrenergic stimulation from the central nervous system, and a highly ...
Leslie P. Kozak, Robert A. Koza
openaire +3 more sources
Brown adipose tissue and lipid metabolism
Current Opinion in Lipidology, 2018Purpose of review This article explores how the interplay between lipid metabolism and thermogenic adipose tissues enables proper physiological adaptation to cold environments in rodents and humans. Recent findings Cold exposure triggers systemic changes
J. Heeren, L. Scheja
semanticscholar +1 more source
Brown Adipose Tissue. Interscapular Brown Adipose Tissue of the Rat
1985Brown or multilocular adipose tissue is relatively infrequent in man and is found predominantly in newborns. It occurs in the neck, armpit (Fig. A1), in the vicinity of the subclavian artery (Fig. A2) and kidney (Fig.A3), dorsal skin, mediastinum (Fig. A4), and mesenteries.
openaire +2 more sources
2014
Most of white and brown adipocytes, in spite of their well-known different functions: i.e. storing energy (white) and thermogenesis (brown), are contained together in visceral and subcutaneous depots (adipose organ) in all mammals including human. A growing body of evidence suggests that the reason for this anatomical mixture could reside in the fact ...
openaire +2 more sources
Most of white and brown adipocytes, in spite of their well-known different functions: i.e. storing energy (white) and thermogenesis (brown), are contained together in visceral and subcutaneous depots (adipose organ) in all mammals including human. A growing body of evidence suggests that the reason for this anatomical mixture could reside in the fact ...
openaire +2 more sources
2015
The second messenger cyclic guanosine monophosphate (cGMP) is a key mediator in physiological processes such as vascular tone, and its essential involvement in pathways regulating metabolism has been recognized in recent years. Here, we focus on the fundamental role of cGMP in brown adipose tissue (BAT) differentiation and function.
Christopher J. Larson +2 more
openaire +2 more sources
The second messenger cyclic guanosine monophosphate (cGMP) is a key mediator in physiological processes such as vascular tone, and its essential involvement in pathways regulating metabolism has been recognized in recent years. Here, we focus on the fundamental role of cGMP in brown adipose tissue (BAT) differentiation and function.
Christopher J. Larson +2 more
openaire +2 more sources
The Origins of Brown Adipose Tissue
New England Journal of Medicine, 2009Adipocytes that make up brown fat have two disparate lineages; one seems more closely related to muscle than to white adipose tissue.
openaire +3 more sources
Brown adipose tissue in humans
International Journal of Obesity, 2010Obesity is endemic in many regions of the world and a forerunner of several serious and sometimes fatal diseases such as ischemic heart disease, stroke, kidney failure and neoplasia. Although we know its origin--it results when energy intake exceeds energy expenditure--at present, the only proven therapy is bariatric surgery.
openaire +3 more sources