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The microprotein C16orf74/MICT1 promotes thermogenesis in brown adipose tissue. [PDF]

open access: yesEMBO J
Dinh J   +10 more
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Brown Adipose Tissue

Journal of Perinatal & Neonatal Nursing, 2011
A constant body temperature can only be maintained when the rate of heat dissipation equals the rate of heat loss. Thermoregulatory heat production mechanisms compensating heat loss are classically categorized as shivering and non-shivering thermogenesis.
Martin Klingenspor, Tobias Fromme
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The Importance of Brown Adipose Tissue

New England Journal of Medicine, 2009
To the Editor: In the April 9 issue, van Marken Lichtenbelt et al., Cypess et al., and Virtanen et al. report on functioning supraclavicular brown adipose tissue in adult humans. Van Marken Lichtenbelt et al. conclude that brown-adipose-tissue activity induced by exposure to cold is impaired in overweight healthy subjects, and Cypess et al., using ...
Timmons, James A, Pedersen, Bente K
openaire   +3 more sources

Brown adipose tissue in humans

Current Opinion in Lipidology, 2011
Human brown adipose tissue (BAT) has recently found to be functionally active in adults. The purpose of this review is to chart the importance of BAT in the light of recent publications in humans.After publication of the direct evidence of functional BAT in human adults the original findings in human studies have been sparse.
Virtanen, KA, Nuutila, P
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Bioenergenetics of brown adipose tissue

Lipids, 1970
AbstractExamination of the effect of 2,4‐dinitrophenol (DNP) in vivo on the brown adipose tissue of cold‐exposed rats as well as the effect of DNP and dicumarol in vitro, indicates that brown fat does possess a functional electron transport‐coupled phosphorylating system.
B A, Horwitz, P A, Herd, R E, Smith
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The Ontogeny of Brown Adipose Tissue

Annual Review of Nutrition, 2015
There are three different types of adipose tissue (AT)—brown, white, and beige—that differ with stage of development, species, and anatomical location. Of these, brown AT (BAT) is the least abundant but has the greatest potential impact on energy balance.
Michael E. Symonds   +2 more
openaire   +2 more sources

Brown adipose tissue and aging

Current Opinion in Clinical Nutrition and Metabolic Care, 2011
Brown adipose tissue (BAT) was thought to be a tissue with physiological importance early in life (maintenance of body temperature) and to disappear after birth. Recent studies using functional imaging have identified the presence of BAT activity throughout life.
Lecoultre Virgile, Ravussin Eric
openaire   +2 more sources

Brown Adipose Tissue

2022
The role of brown adipose tissue in humans is still a matter of debate: Does it play a substantial role in metabolic diseases, or not? The settling of this discussion requires clinical trials, generally including noninvasive imaging techniques, in order to assess the metabolic activity of brown adipose tissue.
Paulus, Andreas, Bauwens, Matthias
openaire   +2 more sources

The Genetics of Brown Adipose Tissue

2010
Brown adipose tissue is highly differentiated and has evolved as a mechanism for heat production based upon uncoupling of mitochondrial oxidative phosphorylation. Additionally, large amounts of lipid can be stored in the cells to provide fuel necessary for heat production upon adrenergic stimulation from the central nervous system, and a highly ...
Leslie P, Kozak, Robert A, Koza
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